24 citations
,
September 2023 in “Science Advances” In this study, deleting the gene Mettl3 in mouse epidermal progenitors resulted in impaired epithelial development and self-renewal, highlighting m6A's crucial role in regulating chromatin modifiers and maintaining normal epithelial tissue function.
22 citations
,
August 2020 in “Cells” This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.
11 citations
,
April 1993 in “PubMed” In this study, trichocytes were shown to have potential for alternative differentiation, with mesenchymal cell influences playing a critical role in determining this process.
7 citations
,
October 2016 in “American Journal of Dermatopathology” This report discusses a 77-year-old man with primary onycholemmal carcinoma, a rare nail bed tumor, emphasizing its slow growth, diagnostic challenges, and treatment typically involving surgical removal.
7 citations
,
January 1996 in “In Practice” This article highlights causes of otitis externa in small animals and proposes an investigative approach; it reports no new findings.
6 citations
,
September 2012 in “Our Dermatology Online” This review discusses the off-label uses of retinoids in dermatology, focusing on oral isotretinoin and acitretin, and reports no new clinical results.
1 citations
,
May 2024 in “Cureus” In this case study, the combination therapy of isotretinoin and rifampicin was reported to effectively improve symptoms in a 58-year-old female patient with folliculitis decalvans, suggesting this approach may warrant further investigation for treating this challenging condition.
1 citations
,
December 2019 This study found that bimatoprost eye drops significantly increased eyelash length, thickness, pigmentation, and the number of eyelashes per follicle in rabbits within one month.
August 2025 in “BMC Genomics” In this study, researchers found distinct gene expression patterns in Standardbred trotters capable of racing barefoot, suggesting a genetic basis for hoof strength and identifying specific genes involved in hoof biology, which could enhance equine performance and wellbeing through targeted genetic research.
April 2018 in “Journal of Investigative Dermatology” This article proposes a new classification system for cutaneous adnexal cysts based on their origin in the folliculo-sebaceous unit and sweat glands, aiming to clarify their categorization and origins.
April 2014 in “The FASEB Journal” This study found that maternal hephaestin knockout in mice leads to neonatal hair loss, likely due to low iron levels in the mother's milk.
January 2007 in “Zhonghua shiyan waike zazhi” This study found that cutaneous stem cells in the basal layer of fetal human skin contribute to the development of the epidermis and hair follicles, with specific marker expressions during different stages of skin development.
January 1982 in “Side effects of drugs annual” This review discusses the therapeutic effects of vitamins, highlighting risks such as liver damage from prolonged high doses of vitamin A and hypercalcemia from excessive vitamin D, while noting a case of allergic reaction to vitamin B12.
In this review, the authors highlight a lack of understanding regarding the unique properties of Afro-textured hair, emphasizing the need for scientific collaboration to improve hair care practices and mitigate scalp issues.
45 citations
,
January 1986
April 2018 in “Journal of Investigative Dermatology” This study found that keratin filament networks in SG1 cells of mice undergo dynamic changes during cornification, impacting the barrier function of the stratum corneum.
7 citations
,
January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry” 81 citations
,
January 1987 in “Current topics in developmental biology/Current Topics in Developmental Biology” Keratins change and are modified differently in skin layers and body parts.
56 citations
,
January 1977 22 citations
,
January 1990 375 citations
,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” This review examines the process of cornification as a mode of programmed cell death and outlines how keratinocytes activate anti-cell death mechanisms to maintain epidermal homeostasis, but reports no new results.
28 citations
,
April 1996 in “Cell biology international” This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.
7 citations
,
January 1990 April 1996 in “Journal of Dermatological Science” 7 citations
,
January 1988 7 citations
,
March 1993 in “International Journal of Oncology” This study found that the keratin expression in basal cell carcinoma resembles that of the pilosebaceous apparatus, with uniform presence of certain keratins in all cases.
23 citations
,
February 1993 in “Journal of Investigative Dermatology” 87 citations
,
November 2002 in “Journal of Investigative Dermatology” 91 citations
,
December 2000 in “The journal of cell biology/The Journal of cell biology” This study reports that expressed mouse type Ia and type IIa trichocyte keratins were successfully assembled into intermediate filaments in vitro, while also suggesting that disulfide bond cross linking enhances their stability.
8 citations
,
July 2004 in “Journal of morphology” This study explored the structure and keratin composition of marsupial hairs, finding similarities in keratin localization to hairs in placental mammals, and highlighting potential roles of trichohyalin and transglutaminase during hair development and shedding.