22 citations
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August 2015 in “PloS one” This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.
This review discusses potential cosmeceutical treatments for hair loss, including ingredients like procyanidins and isoflavones, but does not present new clinical outcomes; the authors highlight the promise of further research.
1 citations
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January 2016 in “Frontiers in Bioengineering and Biotechnology” This study reports that keratin-based materials derived from human hair have potential for use in tissue engineering, showing promising bioactivity and mechanical support in preliminary evaluations.
This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.
8 citations
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May 2020 in “International journal of biological macromolecules” In this study, researchers evaluated the binding of keratin-associated proteins and α-keratins to human hair fibers, finding that chemical preactivation significantly enhanced binding to natural hair, while perming altered binding characteristics and increased penetration depth.
47 citations
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September 2011 in “Acta biomaterialia” This study observed that increasing the γ-kerateine content in meta-kerateine materials led to reduced elasticity, solidity, and hydrolytic stability, and decreased hepatocyte attachment support.
January 2024 in “Molecules (Basel. Online)” In this study, researchers examined juglone's potential as a restoring agent for hair keratin damaged by permanent or bleaching treatments, finding that juglone formed Michael adducts with cysteine residues, leading to a more regular hair surface as observed via IR spectroscopy and SEM analysis.
13 citations
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December 2019 in “Nutrients” In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.
March 2005 in “International Journal of Cosmetic Science” A new method helps understand hair shine and various products improve hair care.
18 citations
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October 2018 in “Nutrients” This study found that Annurca apple polyphenolic extracts reprogram hair follicle metabolism in mice, enhancing mitochondrial activity and keratin production while inhibiting some metabolic pathways.
2 citations
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September 2020 in “Biomedical materials” This study found that recombinant human hair keratin proteins K31 and K81 show greater potential for inducing skin cell differentiation compared to natural keratin coatings.
30 citations
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March 2019 in “Archives animal breeding/Archiv für Tierzucht” In this study, variation in the KRTAP15-1 gene in goats was linked to changes in cashmere fibre diameter, with specific variants showing dominant or recessive effects.
27 citations
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September 2017 in “Journal of Medicinal Food” In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.
8 citations
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July 2011 in “Animal science journal” The researchers reported that keratin 33A is a structural protein specific to goat cashmere hair, with increased winter expression in high-cashmere-producing breeds.
26 citations
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June 2010 in “Electrophoresis” This study reported advances in identifying low-abundance proteins in wool by using fractionation techniques to reduce the dominance of intermediate filament proteins, improving the understanding of the wool proteome.
July 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, a liposomal-encapsulated Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss over 180 days, showing enhanced hair density, thickness, growth rate, and tensile strength compared to placebo, with no related adverse events reported.
18 citations
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November 2016 in “Transgenic research” This study found that transgenic cashmere goats overexpressing thymosin beta-4 have a higher secondary to primary hair follicle ratio, suggesting potential for increased cashmere yield.
November 2023 in “Borneo Journal of Pharmacy” In this study, researchers used scanning electron microscopy to analyze hair damage from 3% hydrogen peroxide and UVB radiation, observing that Caesalpinia sappan hair tonic formulations coated and interacted with the hair cuticle, potentially modifying hair fiber damage.
December 2022 in “Deleted Journal” In this study, topical application of keratin extract from wool promoted hair growth in mice by reducing the time for initiation and completion of growth phases and improving hair quality.
This review discusses advancements in regenerative medicine for hair loss treatments, highlighting stem cell techniques for rejuvenating or creating hair follicles, but provides no new clinical results.
54 citations
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January 2013 in “Journal of Biological Macromolecules” This study proposes a new method to selectively isolate keratin-associated proteins and keratin from human hair, suggesting that KAPs may support keratin fibers in hair structure.
This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.
February 2025 in “BMC Veterinary Research” This study examined proteomic changes in Inner Mongolia cashmere goat skin, finding 631 proteins differentially regulated during hair growth stages; key keratin proteins, crucial for hair follicle development, were localized in secondary hair follicles.
April 2026 in “Biomolecules” This study reported that discarded squid ink was used to develop a high-performance, environmentally friendly hair dye that offers a stable deep black color, UV protection, and preserves hair structure, while showing excellent biosafety in lab tests.
May 2024 in “Proteome science” This study found that the PLEE method increased hair protein extraction efficiency threefold and that bleaching hair reduced the coverage of keratin and associated proteins, leading to poorer hair quality, though it did not affect the overall protein identification.
January 2024 in “Seven Editora eBooks” This paper reviews various techniques for measuring the physical and mechanical properties of human hair fibers, emphasizing their importance in developing effective cosmetic products.
11 citations
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February 2018 in “Amino acids” This study found that homocysteine-keratin accumulation in human hair increases towards the tips, linked to copper/iron-catalyzed demethylation of methionine, and may contribute to keratin damage.
63 citations
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February 2017 in “ACS biomaterials science & engineering” In this study, polydopamine emerged as a safe and effective alternative to traditional hair dyes like PPD for dyeing gray hair permanently, showing resistance to detergents and causing less toxicity and hair loss in mice.
April 2014 in “Journal of Aesthetic Nursing” This article provides descriptive results indicating high client satisfaction and good tolerance associated with mesotherapy in treating hair loss, based on the author's personal experience with clients.
This study used proteomic profiling to reveal significant individual and site-specific differences in human hair shaft proteins, which may improve the differentiation of hair based on ethnic origin and individual identity.