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Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Stress may trigger hair loss by affecting immune protection in hair follicles.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Rhamnose may help hair growth and pigmentation, making it a potential treatment for hair loss.

Human skin cells can create new hair follicles when transplanted into mice.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.

New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Valproic acid can cause hair loss when taken orally but may promote hair growth when applied topically.

Tiny needles with valproic acid can effectively regrow hair.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Improving the environment and cell interactions is key for creating human hair in the lab.

Magnesium Silicate Sprays help heal burn wounds and regrow skin features better than commercial products.

Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.

Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.