January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
May 2009 in “Medical and surgical dermatology/Medical & surgical dermatology” Hair and nail conditions can stabilize or improve over time, and new treatments show promise.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Topical 5α-reductase inhibitor helps counteract hair loss and stabilize it.
25 citations,
October 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.
December 2023 in “Journal of molecular structure” Hair treatments and dehydration affect hair's lipid and protein behavior, influencing its flexibility and appearance.
375 citations,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
22 citations,
August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
February 1999 in “The anatomical record” Two mouse mutants have defective hair cuticle cross-linking.
September 2022 in “Cosmetics” 19 citations,
July 2020 in “EBioMedicine” A gene variant increases the risk of a type of hair loss by affecting hair protein production.
14 citations,
June 2020 in “BMC genomics” The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.
7 citations,
June 2022 in “Frontiers in Veterinary Science” Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.
7 citations,
August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
7 citations,
January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” NIPP1 is important for healthy skin and could help treat skin inflammation.
3 citations,
July 2023 in “Acta Biomaterialia” PepACS offers a safer, eco-friendly way to perm, dye, and repair hair.
September 2024 in “JAMA Dermatology” Low-dose metformin may help hair regrowth and reduce inflammation in CCCA.
September 2024 in “Heliyon” Repeated hair dyeing significantly damages hair.
September 2023 in “Biomedical Optics Express” New imaging techniques show testosterone delays hair growth and shrinks follicles in mice, but have limited depth for viewing.
Different androgen concentrations affect wool-related gene expression differently in Hetian and Karakul sheep breeds.
62 citations,
December 2007 in “Journal of biological chemistry/The Journal of biological chemistry” A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.
21 citations,
July 2022 in “Orphanet journal of rare diseases” New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
8 citations,
January 2023 in “International journal of molecular sciences” Transglutaminase activity is important for skin and is found in both mammals and birds.
5 citations,
June 2017 in “in Vivo” Vitamin C deficiency changes gene expression, affecting skin and hair health.
3 citations,
March 2023 in “Biology” Genes affecting wool fiber thickness in Angora rabbits were identified, which could help breed finer wool.
3 citations,
September 2014 in “SpringerPlus” Human hair loss may have evolved to help increase brain size.
1 citations,
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Keeping β-catenin levels high in mammary cells disrupts their development and branching.
Human hair can almost fully recover its structure within about 1,000 minutes after being stretched.
October 2022 in “International Journal of Molecular Sciences” Fish collagen peptides can significantly promote hair growth.
August 2022 in “International Journal of Molecular Sciences” DNA methylation controls lncRNA2919, which negatively affects hair growth.
426 citations,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.