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The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Cathepsin L is essential for normal hair growth and development.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Oxidative stress contributes to hair graying and loss as we age.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

KGF and activin are crucial for skin healing and repair.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Activating TRPV3 stops human hair growth.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Skin has specialized touch receptors that can tell different sensations apart.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.