August 2023 in “Drug Delivery and Translational Research” Human hair keratin was used to create a scaffold that could help with skin repair.
December 2022 in “Communications biology” December 2022 in “Communications biology” A specific gene mutation causes monilethrix in this family, and minoxidil treatment improves hair condition.
49 citations,
April 2010 in “International Journal of Cosmetic Science” The study examined very long human hair (over 2.4 m) to understand the natural ageing process of hair keratin fibers using various evaluation methods. It focused on hair that had not been exposed to chemical treatments like bleaching or dyeing. The findings showed that ageing begins with the abrasion of the cuticle while the cortex remains intact up to about 1 m from the root, maintaining shine, hydrophobicity, and friction characteristics. Beyond this point, significant cuticle damage occurs, correlating with a decline in ceramides, 18-Methyl Eicosanoic Acid (18-MEA), and keratin-associated proteins, leading to a decrease in mechanical and optical properties. This research provided a detailed 'damage scale' of hair ageing, which could aid in developing targeted hair care products.
The KRTAP36-2 gene in sheep affects wool yield.
49 citations,
August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
5 citations,
February 2007 in “Cytology and genetics” 1 citations,
January 2021 in “Research journal of pharmacy and technology” 215 citations,
November 2000 in “Journal of Investigative Dermatology” The system allows precise control of gene expression in mouse skin, useful for studying skin biology.
76 citations,
December 2011 in “Journal of Cell Science” Different keratin types have unique amino acid patterns that are evolutionarily conserved.
69 citations,
January 2015 in “Cell & tissue research/Cell and tissue research” Keratin mutations cause skin diseases and could lead to new treatments.
53 citations,
September 2004 in “American journal of medical genetics. Part C, Seminars in medical genetics” Mutations in keratin genes cause cell fragility and various skin disorders.
47 citations,
September 2011 in “Acta biomaterialia” Protein composition greatly affects the function of keratin biomaterials.
20 citations,
June 2012 in “British Journal of Dermatology” Bleaching hair damages protein structure, especially keratin, leading to weakened hair.
14 citations,
January 2015 in “Genetics and molecular research” The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.
13 citations,
May 2001 in “Current problems in dermatology” Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
11 citations,
January 1987 in “Electrophoresis” Keratin proteins are consistent across different hair types from the same person.
9 citations,
January 1989 in “Sen'i Gakkaishi” Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.
8 citations,
July 2004 in “Journal of morphology” Marsupial hair structure and keratin distribution are similar to placental mammals.
7 citations,
May 2021 in “Applied sciences” Proteins like BSA and keratin can effectively style hair and protect it, offering eco-friendly alternatives to chemical products.
3 citations,
December 2018 in “Routledge eBooks” Hair is made of strong keratin fibers that protect against the environment.
2 citations,
February 2021 in “Journal of comparative pathology” Sheep with chronic Sarcoptes scabiei dermatitis have altered keratin expression in their skin.
2 citations,
August 2020 in “Scientific reports” Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
1 citations,
August 2020 in “CRC Press eBooks” Hair growth can be influenced by manipulating keratin and growth factor genes.
1 citations,
February 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” Irwin Freedberg made significant contributions to understanding keratin proteins in dermatology.
May 2024 in “Proteome science” Bleaching damages hair by reducing the quality of keratin and keratin-associated proteins.
Black hair's diversity in patterns and textures is influenced by follicle shape and keratin, and it holds cultural, artistic, and mathematical significance.
July 2023 in “Indian Journal of Animal Health” FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.