74 citations,
October 1998 in “Journal of biological chemistry/The Journal of biological chemistry” The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
January 2019 in “Journal of cosmetology & trichology” L-Cystine and L-Cystine with Kera-Diet® safely improved hair and nail quality in healthy women.
32 citations,
February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
1 citations,
October 2022 in “Bioengineering” Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.
51 citations,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
8 citations,
March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
January 2024 in “Molecules (Basel. Online)” Juglone from walnut extracts may help repair damaged hair.
January 2013 in “Sen'i Gakkaishi” Microfibrils are key for permanent waves, and hydrolyzed keratin improves wave formation and hair condition.
February 2024 in “ACS applied bio materials” Keratin microspheres might help hair grow.
517 citations,
February 2010 in “Materials” Keratin from hair and wool is used in medical materials for healing and drug delivery.
186 citations,
December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
115 citations,
August 2014 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” Human hair keratin can be used in many medical applications.
100 citations,
December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
92 citations,
April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.
65 citations,
September 2014 in “BMC genomics” Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.
45 citations,
December 2007 in “The FASEB journal” There are two types of stem cells in rodent hair follicles, each with different keratin proteins.
38 citations,
December 2020 in “International journal of biochemistry & cell biology” Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
35 citations,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
22 citations,
August 2015 in “PloS one” Keratin from hair binds well to gold and BMP-2, useful for bone repair.
15 citations,
January 2018 in “Advances in experimental medicine and biology” Keratin proteins are crucial for hair growth and structure.
14 citations,
January 2015 in “Genetics and molecular research” The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.
13 citations,
July 2017 in “Biopolymers” Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.
10 citations,
November 2021 in “International journal of molecular sciences” Sheep and goat hair fibers are complex due to keratin-associated proteins, which are important for fiber properties and growth.
10 citations,
January 2010 in “International journal of trichology” Keratin-associated proteins are part of the developing hair fiber cuticle.
9 citations,
January 1989 in “Sen'i Gakkaishi” Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.
7 citations,
May 2021 in “Applied sciences” Proteins like BSA and keratin can effectively style hair and protect it, offering eco-friendly alternatives to chemical products.
6 citations,
January 2022 in “Gene” Scientists found 53 keratin genes in yaks that are important for hair growth and share similarities with those in other animals.
5 citations,
September 2018 in “International journal of genomics” Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.
4 citations,
January 2020 in “Genes” The KRTAP21-2 gene affects wool length and quality in sheep.
3 citations,
March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.