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    Glossary Keratin 2

    protein providing structural strength to skin, hair, and nails

    Keratin 2 (KRT2) is a type of protein found in the outer layer of the skin, hair, and nails. It plays a crucial role in providing structural strength and resilience to these tissues, helping to protect them from damage and wear. Mutations in the KRT2 gene can lead to skin disorders such as ichthyosis bullosa of Siemens, which is characterized by blistering and scaling of the skin.

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    Research 30 of 1000+

    1. Binding Interactions of Keratin-Based Hair Fiber Extract to Gold, Keratin, and BMP-2 PloS one · 2015 · 22 citations
    2. The Mean Staple Length of Wool Fibre Is Associated with Variation in the Ovine Keratin-Associated Protein 21-2 Gene Genes · 2020 · 4 citations
    3. Identification of the Keratin-Associated Protein 22-2 Gene in the Capra hircus and Association of Its Variation with Cashmere Traits Animals · 2023 · 1 citations
    4. Histopathological Analysis on keratin2-6 g Expression in Hair Mutant Mouse Hague Proceedings of The Japanese Society of Animal Models for Human Diseases · 2002
    5. Characterization of the Human Hair Keratin–Associated Protein 2 (KRTAP2) Gene Family Journal of Investigative Dermatology · 2012 · 52 citations
    6. Corrigendum to “Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro” [Eur. J. Cell Biol. (2010) 769–777] European Journal of Cell Biology · 2012 · 1 citations
    7. Ovine KRTAP36-2: A New Keratin-Associated Protein Gene Related to Variation in Wool Yield Genes · 2023
    8. Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion (Adv. Healthcare Mater. 12/2026) Advanced Healthcare Materials · 2026
    9. Re: “Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial” by Tenore <i>et al.</i> (<i>J Med Food</i> 2018;21:90–103) Journal of Medicinal Food · 2019 · 2 citations
    10. One‐Step Tunable Human Hair Keratin Gradient Hydrogel with Antibacterial Activity for Tissue Engineering (Small 52/2025) Small · 2025
    11. Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair (vol 8, pg 241, 2008) 2009
    12. AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    13. Peer Review #2 of "Human hair shaft proteomic profiling: individual differences, site specificity and cuticle analysis (v0.1)" 2014
    14. George Ernest Rogers 1927–2021 2023
    15. Scientific Opinion on the substantiation of a health claim related to KF2BL20 and maintenance of normal hair pursuant to Article 13(5) of Regulation (EC) No 1924/2006 EFSA journal · 2012 · 1 citations
    16. J. Cosmet. Sci., 59, 203-215 (May/June 2008) �Effects of permanent waving on changes of protein and physicomorphological properties in human head hair International Journal of Cosmetic Science · 2009
    17. Symposium Proceedings of the 4th Intercontinental Meeting of Hair Research Societies: “The World of Hair 2004” Journal of Investigative Dermatology Symposium Proceedings · 2005
    18. Merkel cell differentiation in trichoblastoma Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · 1998 · 34 citations
    19. Merkel Cells in Hyperplastic and Neoplastic Lesions of the Skin Dermatology · 1998 · 24 citations
    20. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008 · 115 citations
    21. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    22. Seasonal Gene Expression Profile Responsible for Hair Follicle Development in Angora Goats 2023
    23. 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks 2022
    24. An interview Drs. Felix Brockschmidt and Markus Nöthen about the genetics of androgenetic alopecia Hair transplant forum international · 2009
    25. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
    26. Investigation of pH effect on cationic solute binding to keratin and partition to hair International Journal of Cosmetic Science · 2017 · 3 citations
    27. Upcycling waste hair and feathers derived keratin into intact cortical cell-derived micro-units via periodate oxidation: Applications & life cycle assessment International Journal of Biological Macromolecules · 2026
    28. Eczema-Like Psoriasiform Skin Reaction Related to Brazilian Keratin Treatment 2026
    29. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001 · 272 citations
    30. Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration Development · 2013 · 60 citations