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This study found that inhibiting the Mitochondrial Pyruvate Carrier in human scalp hair follicles caused metabolic stress that halted cell proliferation and disrupted key signaling pathways, with these effects partially reversed by an integrated stress response inhibitor.

This study revealed that nestin-expressing progenitor cells capable of becoming ORS keratinocytes are present during both hair follicle development and in adult hair follicles.

This study found that nestin-expressing unipotent progenitor cells capable of differentiating into outer root sheath keratinocytes are present during hair follicle development and in adult hair follicles.

This study reports the first keratin gene mutation affecting the tail domain, leading to a unique cytoskeletal abnormality and severe epidermal hyperkeratosis, highlighting the tail domain's critical role in keratin organization.

This study found that alkylation of kerateine cysteine residues created a cell-compatible method for controlling hydrogel erosion rates and therapeutic agent release in keratin-based systems.

Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.

This study found that the promoter region of the sheep KRTAP11-1 gene drives specific transcriptional activity in wool follicles, suggesting it may regulate hair keratinocyte specificity.

This study found that cashmere has a significantly smaller mean fiber diameter compared to sheep and goat wool, and identified key proteins that may influence this difference.

This study identified genes potentially involved in the development and differentiation of skin appendages in Atelerix albiventris, noting significant enrichment of immune-related genes in hair-type tissues.

This study found that fibroblast growth factor 5 may enhance Cashmere goat hair growth by altering the expression of specific genes related to keratin and keratin-associated proteins.

This study describes a method for labeling and tracking hair follicle stem cells in mouse skin using a Cre/lox recombination system with tamoxifen, providing insights into stem cell behavior and contribution to tissue regeneration.

This study reported that in a mouse model, Negative Pressure Wound Therapy promotes wound healing by modulating inflammatory responses and increasing dickkopf-related protein 1, which encourages the differentiation of Hair Follicle Stem Cells into epidermal cells.

This study identified mutations in the SREBF1 gene that impair SREBP1 function, potentially contributing to IFAP syndrome by affecting skin, hair, and eye development.

The researchers found that HOXC13 regulates different keratin proteins in a mixed manner, with certain SNPs impeding this regulation, while also demonstrating negative-feedback by HOXC13 and positive regulation by LEF1 and melatonin on the HOXC13 promoter.

This study found that testosterone administration reduced the expression of uterine receptivity molecules in ovariectomized rats, which may negatively affect early pregnancy establishment and female fertility.

The researchers reported that inhibiting 11β-HSD1 activity in human dermal papilla cells may reduce the negative effects of glucocorticoids on hair growth, suggesting potential treatment for stress-related hair loss.

Homemade hair treatments can significantly lower drug levels in hair, possibly causing false-negative drug tests.

This study suggests that hair follicle stem cells from transgenic mice can improve nerve regeneration and function, highlighting their potential as an autologous source for regenerative medicine.

CD34 is a marker for isolating stem-like cells in mouse hair follicles.

This study found that Ber-EP4 immunoreactivity is present in specific areas of hair follicles across different stages of the hair cycle, particularly in the secondary hair germ, but not in mature anagen follicles.

This study found that K15 is a useful marker for investigating the role of stem cells in canine hair follicle tumours, while nestin is not optimal.

This study reveals an antagonistic competition between BMP and Wnt signaling within stem cells, influencing their fate towards hair germ characteristics based on the BMP/Wnt activity ratio.

This study reports that human hair follicle stem cells express different surface markers than mouse stem cells, facilitating their isolation and potentially aiding in the development of cell-based skin treatments.

This study found that coculturing human hair follicle keratinocyte stem cells with dermal papilla cells increased expression of the hair-specific keratin 6hf gene, which requires β-catenin/lef-1 signaling for hair differentiation.

In this study, deleting the Igf1 receptor in specific skin cells of mice affected hair follicle cycling but not overall skin health, suggesting Igf1r's role in hair cycle regulation through Bmp-4 activation.

In this study, researchers found that the KLHL24-ΔN28 protein variant disrupts hair follicle stem cells in a mouse model, leading to premature hair loss by degrading keratin 15.

This study found that human induced pluripotent stem cells differentiated precisely to express certain markers during a specific window could enable successful hair follicle generation when transplanted.

In this study, transgenic mice expressing a truncated form of latent transforming growth factor-β-binding protein exhibited altered hair cycles due to increased active transforming growth factor-β, impacting keratinocyte proliferation and hair cycle phases.

This study found that when human hair follicles were grafted onto mice, they progressed through dystrophic stages and returned to normal growth, with stem cells aiding in recovery.

This study mapped a spontaneous mouse hair mutation, "hague," to keratin genes on chromosome 15 but found no gene mutations in hague mice.