78 citations
,
June 1989 in “The Journal of dermatologic surgery and oncology” This article reviews acne keloidalis in young black men, describes its clinical and histopathological characteristics, and highlights surgical therapy approaches despite the uncertain etiology of the condition.
72 citations
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November 2000 in “Archives of Dermatology” This study found that excision with primary closure is an effective surgical treatment for extensive acne keloidalis nuchae, with good cosmetic results and minimal recurrence observed among patients.
68 citations
,
July 2016 in “Dermatology and Therapy” This review highlights that light and laser therapies, such as the 1064-nm Nd:YAG and 810-nm diode lasers, may offer significant improvement for acne keloidalis nuchae with minimal side effects, though larger trials are needed.
66 citations
,
October 2003 in “Dermatologic clinics” Excision and laser techniques can effectively treat acne keloidalis nuchae.
59 citations
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December 2016 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the clinical features and treatment challenges of acne keloidalis nuchae, a form of chronic scarring folliculitis, and reports no new results.
49 citations
,
March 2014 in “Dermatologic clinics” This article discusses the causes, development, treatment, and prevention strategies for pseudofolliculitis barbae and folliculitis keloidalis nuchae, but reports no new clinical results.
40 citations
,
September 2012 in “European Journal of Dermatology” This study found that long pulsed Nd-YAG laser treatment significantly improved acne keloidalis nuchae by reducing inflammation and hair follicles, with early intervention yielding the best results.
40 citations
,
May 2010 in “American Journal of Clinical Dermatology” This study reports that four Indian patients with acne keloidalis nuchae also exhibited acanthosis nigricans, suggesting a potential link to metabolic syndrome, though further research is needed to confirm this association.
37 citations
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September 2005 in “Australasian Journal of Dermatology” This case report describes a 27-year-old man with a unique association of keratosis follicularis spinulosa decalvans and acne keloidalis nuchae, successfully treated with oral isotretinoin.
35 citations
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January 2008 in “American Journal of Clinical Dermatology” This case report further supports the association of keratosis follicularis spinulosa decalvans with acne keloidalis nuchae and tufted hair folliculitis.
27 citations
,
June 2017 in “International Journal of Dermatology” This study found that acne keloidalis nuchae was associated with pseudofolliculitis barbae, chronic scalp folliculitis, and aspects of the metabolic syndrome, particularly hypertension, in the examined population.
24 citations
,
October 2007 in “Clinical and experimental dermatology” This case report describes two men with acne keloidalis nuchae who experienced successful outcomes with excision followed by secondary intention healing, resulting in good cosmetic results and minimal recurrence.
23 citations
,
January 2024 in “Journal of Investigative Dermatology” In this study, researchers used advanced RNA sequencing techniques to discover that communication between specific fibroblast and myeloid cell populations may play a role in acne keloidalis, and found that corticosteroid injections could significantly reduce disease activity and gene expression related to these cells.
19 citations
,
October 2017 in “Dermatologic Surgery” In this study, 755-nm alexandrite laser treatment significantly reduced acne keloidalis nuchae lesions in male patients, improving quality of life and showing low recurrence rates, with temporary hair loss as a reversible complication.
12 citations
,
May 2018 in “Journal of Cosmetic and Laser Therapy” This study found that Er:YAG laser treatment resulted in a statistically significant reduction in papules, plaques count, size, and consistency in men with acne keloidalis nuchae, showing slightly more improvement than long-pulsed Nd:YAG laser therapy.
9 citations
,
June 2019 in “JAAD case reports” This report discusses laser hair removal for acne keloidalis nuchae, noting generally favorable outcomes but variability in lesion responsiveness and a need for standardized assessment criteria; it reports no new results.
6 citations
,
April 2016 in “Australasian journal of dermatology” Renal transplant patients on tacrolimus and sirolimus may develop acne keloidalis nuchae.
5 citations
,
April 2021 in “International Journal of Homoeopathic Sciences” This article reviews Acne Keloidalis Nuchae and presents a successful treatment case using Homoeopathy, emphasizing the need for individualized treatment approaches, but reports no new clinical results.
2 citations
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September 2023 in “JAAD Case Reports” This article discusses the chronic inflammatory skin diseases acne keloidalis nuchae and dissecting cellulitis of the scalp, focusing on their shared etiology and differing progression, and reports no new clinical findings.
1 citations
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September 2023 in “International Journal of Dermatology” In this study conducted at a tertiary dermatological clinic, researchers identified and described the clinical, dermoscopic, and histopathological features of preclinical folliculitis keloidalis, including novel dermoscopic findings such as perifollicular scale, which was associated with fibrosis.
1 citations
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August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.
January 2026 in “Journal of Cutaneous Immunology and Allergy” In this case report, a young Japanese man was diagnosed with scalp IgG4-related disease, which mimicked acne keloidalis nuchae but was identified by histopathology and elevated serum IgG4 levels as a systemic fibroinflammatory disorder, highlighting the importance of differential diagnosis in atypical scarring alopecia.
September 2025 in “The health sciences AUS.” This review discusses the efficacy and safety of intralesional triamcinolone acetonide for treating acne keloidalis nuchae, highlighting its significant effectiveness with rare side effects when used properly.
June 2025 in “British Journal of Dermatology” This review highlights that acne keloidalis nuchae notably affects men with afro-textured hair and results in scarring and hair loss, underscoring the need for improved diagnosis and treatment strategies due to its significant psychosocial impact and high recurrence rates following current therapies.
In this case report, an African American male with signs of acne keloidalis nuchae highlights the condition's chronic nature and need for early intervention to minimize permanent scarring and its psychosocial impact.
January 2024 in “Dermatologic therapy” This review describes the characteristics and treatment of acne keloidalis nuchae, focusing on related conditions and available therapeutic approaches, but presents no new clinical findings.
July 2022 in “SKIN The Journal of Cutaneous Medicine” This case report presents the first successful treatment of acne keloidalis nuchae with a combination of halobetasol 0.01% and tazarotene 0.045% lotion.
September 2021 in “CRC Press eBooks” This article discusses the characteristics and pathogenesis of acne keloidalis nuchae among men with coarse curly hair, reviewing its association with factors like chronic inflammation and potential roles for metabolic syndrome and infection. It reports no new results.
June 2021 in “Journal of The American Academy of Dermatology” This study suggests that the "spade sign" is a highly specific histopathologic feature of acne keloidalis, although its absence does not rule out the condition.
July 2018 in “Elsevier eBooks” This review discusses primary neutrophilic cicatricial alopecias, their clinical and histological characteristics, and the importance of early therapeutic intervention to prevent scarring alopecia, reporting no new clinical results.