10 citations
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December 2011 in “PubMed” In this reported case of SAPHO syndrome, methotrexate treatment led to significant clinical improvement after other treatments for skin lesions and arthritis proved less effective.
In this chapter, the authors discuss how microneedling and platelet-rich plasma are effective for cosmetic purposes with minimal downtime, noting potential mild side effects and the necessity for multiple treatments.
Tailored nonsurgical cosmetic procedures are crucial for safely treating diverse skin types, especially skin of color.
40 citations
,
May 2010 in “American Journal of Clinical Dermatology” This study reports that four Indian patients with acne keloidalis nuchae also exhibited acanthosis nigricans, suggesting a potential link to metabolic syndrome, though further research is needed to confirm this association.
16 citations
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October 1979 in “The Journal of Dermatologic Surgery and Oncology” In this report, a 17-year-old boy received successful scalp reduction surgery for alopecia due to a thermal burn, achieving excellent cosmetic results without hypertrophic or keloidal scarring.
6 citations
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July 1976 in “JAMA” This article discusses dermatological issues associated with black skin, such as postinflammatory pigmentation and keloids, and highlights the need for practitioners to understand these racial characteristics; it reports no new clinical results.
April 2024 in “Journal of Pakistan Association of Dermatologists” In this study of male patients with non-curly hair, the researchers observed a significant occurrence of folliculitis nuchae linked to close haircuts and shaving, with treatment effectiveness varying by disease phase and best results seen in early stages.
2 citations
,
June 2012 in “Journal of Cosmetic Dermatology” This article describes using hair transplantation as a novel method to improve the appearance of acne scars, but it reports no clinical results.
1 citations
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December 2011 in “Journal of The American Academy of Dermatology” This book review examines various classification and treatment methods for acne scars, emphasizing the complexity and need for multiple therapeutic approaches, but reports no new clinical results.
305 citations
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March 2018 in “International journal of molecular sciences” In this review, the authors summarize classical and recent insights into the biology and treatment of hypertrophic scars and keloids, concluding that while understanding and strategies have advanced, effective prevention and treatments remain unsatisfactory.
106 citations
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January 2016 in “Journal of Cosmetic Dermatology” This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.
April 2026 in “Biomedical Research and Therapy” This study found that certain genetic variants, specifically CYB5R1 and IL1A, may be linked to different types of acne scarring, with CYB5R1 associated with atrophic scarring and IL1A with fibrotic scarring, indicating a potential polygenic nature of acne scarring.
January 2024 in “International Journal of Homoeopathic Sciences” In this case study, a 29-year-old woman's acne scars improved alongside enhancements in emotional well-being following six months of personalized homeopathic treatment, suggesting potential benefits for individuals unresponsive to conventional therapies, though further research is needed to substantiate these findings.
September 2023 in “International journal of biomedicine” This review evaluated current evidence on minoxidil's potential to treat scars and reported reduced collagen accumulation and fibrosis in various studies, suggesting its antifibrotic effects may benefit wound healing; however, direct studies on acne scars are yet to be conducted.
October 2021 in “The Egyptian Journal of Hospital Medicine ” This study concluded that combination therapies often yield better results for treating atrophic post-acne scars than single treatments.
10 citations
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January 2018 in “Elsevier eBooks” This review discusses the wound healing process and the factors contributing to abnormal scarring after thermal injuries, but it reports no new clinical results.
3 citations
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January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
2 citations
,
January 2022 in “Journal of Cutaneous and Aesthetic Surgery” This study suggests the mechanical effect of injecting a solution is more important than the solution's nature in treating atrophic acne scars, with UBM sonography proposed for objective assessment.
1 citations
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August 2024 in “Journal of Cutaneous and Aesthetic Surgery” In this study, 65% TCA showed better improvement for acne scars compared to 50% GA, but GA may be a safer alternative with fewer adverse effects.
March 2026 in “Frontiers in Cell and Developmental Biology” This meta-analysis found that autologous cell-based therapies, especially stromal vascular fraction, significantly improved atrophic acne scars over control treatments, enhancing both clinical and patient-reported outcomes.
October 2025 in “Dermatology Practical & Conceptual” This source highlights the potential benefits of identifying risk factors and intervening early to mitigate acne scarring and improve quality of life. It also emphasizes the importance of recognizing acne severity predictors to guide preventive strategies and optimize patient outcomes.
December 2024 in “Journal of Cutaneous and Aesthetic Surgery” The researchers observed that dermoscopy is valuable for assessing acne scars and their response to treatment, with shorter-duration scars responding more effectively.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.
78 citations
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June 2021 in “Dermatology and Therapy” This study highlights the evolving understanding of acne's pathophysiology and suggests that targeting pro-inflammatory cytokines such as IL-1β, IL-17, IL-23, and TNFα with biological antibodies may offer new treatment strategies for severe acne and its scars.
64 citations
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January 2004 in “American journal of clinical dermatology” This review describes various types of folliculitis based on their causes, clinical manifestations, and treatments, but reports no new clinical results.
49 citations
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August 2016 in “Aesthetic Surgery Journal” This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.
26 citations
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March 2014 in “Journal of cutaneous medicine and surgery” This study provides evidence-based recommendations for the off-label use of topical vitamin D in treating certain skin conditions, but highlights the need for higher quality studies for further validation.
September 2002 in “Dermatologic Surgery” This article offers guidance for hair transplant surgeons on addressing old or poorly executed transplants, focusing on surgical precision and effective use of limited donor hair to enhance cosmetic outcomes.
16 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review explores new theories, diagnostic tools, and management strategies for primary cicatricial alopecia but reports no new clinical findings.
7 citations
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April 2011 in “Expert review of dermatology” This article reviews practical approaches for managing dermatologic conditions in patients with skin of color and reports no new clinical findings.