May 2022 in “Journal of Asia Pacific Aesthetic Sciences” This paper discusses cases of unpredictable scarring in hair transplant patients and addresses how less invasive techniques like FUE and SMP may mitigate these issues.
5 citations
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April 2021 in “International Journal of Homoeopathic Sciences” This article reviews Acne Keloidalis Nuchae and presents a successful treatment case using Homoeopathy, emphasizing the need for individualized treatment approaches, but reports no new clinical results.
September 2021 in “CRC Press eBooks” This article discusses the characteristics and pathogenesis of acne keloidalis nuchae among men with coarse curly hair, reviewing its association with factors like chronic inflammation and potential roles for metabolic syndrome and infection. It reports no new results.
In this case report, an African American male with signs of acne keloidalis nuchae highlights the condition's chronic nature and need for early intervention to minimize permanent scarring and its psychosocial impact.
January 2016 in “Georg Thieme Verlag eBooks” Hair transplantation in East Asians needs special techniques to ensure natural results and prevent complications due to their unique hair and scalp characteristics.
July 2025 in “Russian Journal of Transplantology and Artificial Organs” This research highlights advancements in reconstructive surgery for managing scars, emphasizing the importance of combined surgical and nonsurgical interventions like platelet-rich plasma and stem cell therapy to prevent and treat thick scar tissue while enhancing functionality and aesthetic outcomes.
305 citations
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March 2018 in “International journal of molecular sciences” In this review, the authors summarize classical and recent insights into the biology and treatment of hypertrophic scars and keloids, concluding that while understanding and strategies have advanced, effective prevention and treatments remain unsatisfactory.
July 2024 in “Journal of Investigative Dermatology” Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.
June 2026 in “Preprints.org” This review examines the mechanisms behind pathological scarring like hypertrophic scars and keloids, highlights the limitations of current treatments, and suggests that biomaterial-enabled delivery of anti-fibrotic statins, such as atorvastatin, may offer a promising therapeutic avenue for managing these scars.
3 citations
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March 1956 in “PubMed” This study discusses a surgical skin planing procedure using new technology and freezing agent that is reported to be a safe, effective treatment for cutaneous defects like pitted acne scars.
65 citations
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March 2018 in “Journal of Dermatological Science” This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.
5 citations
,
May 2022 in “Molecules” This article reviews the literature on the off-label use of botulinum toxin for dermatological conditions, highlighting its potential effectiveness in treating rosacea, anal fissures, Raynaud phenomenon, hypertrophic scars, keloids, and hidradenitis suppurativa.
2 citations
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July 2024 in “International Journal of Transgender Health” This study reviewed literature on dermatological changes in transgender and gender diverse individuals during gender affirming medical transition, identifying risks like acne and hypertrophic scars, and provided tailored care recommendations for health professionals.
January 2025 in “Tanzania journal of health research/Tanzania Journal of Health Research” This research discusses autologous mini-punch grafting, a surgical technique for treating stable, minor vitiligo when non-surgical treatments fail, reporting up to 75% repigmentation success in 78% of treated patients, although complications like cobblestoning and graft rejection may occur.
3 citations
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September 2025 in “Frontiers in Microbiology” This review article proposes a possible skin-gut-fibrosis axis, suggesting that gut microbial metabolites may influence the development of keloids and hypertrophic scars by affecting immune responses and fibrotic signaling pathways, although direct evidence in skin fibrosis remains limited.
January 2025 in “Dermatologic Therapy” This retrospective study reported significant improvements in keloid scars among 60 patients treated with punch excision and superficial X-ray, with lower Vancouver Scar Scale and Patient and Observer Scar Assessment Scale scores a year post-treatment and no severe adverse reactions observed.
15 citations
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November 2024 in “Journal of Advanced Research” In this study, researchers found that miR-3606-3p is significantly downregulated in skin fibrosis and correlates with disease severity, with its ability to inhibit key signaling pathways suggesting potential therapeutic applications for conditions like systemic sclerosis and keloids.
92 citations
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June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This review found that microneedling appears to be a safe and effective option for treating scars and wrinkles, with fewer side effects and shorter recovery time than some other treatments.
81 citations
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January 2000 in “American journal of clinical dermatology” Various treatments can improve post-acne scars, but results vary.
4 citations
,
June 2022 in “Cold Spring Harbor Perspectives in Biology” This review discusses the heterogeneity of dermal fibroblasts in healthy mouse and human skin and reports no clinical results; the authors highlight potential insights into physiological and pathological wound healing.
February 2024 in “International Journal of Dermatology” This report highlights that scientific collaborations have led to a rise in publications focused on African skin and hair, which could inform the development of locally tailored products and awareness campaigns.
December 2023 in “Juan Cuevas eBooks” This source describes the fourth volume of the "Guía de Procedimientos en Cirugía Plástica Reconstructiva" as an essential, expert-compiled reference detailing the latest advanced techniques in reconstructive plastic surgery for surgeons, residents, and professionals in the field.
78 citations
,
June 2021 in “Dermatology and Therapy” This study highlights the evolving understanding of acne's pathophysiology and suggests that targeting pro-inflammatory cytokines such as IL-1β, IL-17, IL-23, and TNFα with biological antibodies may offer new treatment strategies for severe acne and its scars.
34 citations
,
September 2009 in “International Journal of Dermatology” This article reviews the skin effects of anabolic-androgenic steroid use in athletes but reports no clinical results.
Tailored nonsurgical cosmetic procedures are crucial for safely treating diverse skin types, especially skin of color.
This review discusses the complex process of wound healing and emerging areas of interest in wound treatment, reporting no new clinical findings.
17 citations
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July 2014 in “Our Dermatology Online” In this study of elderly patients at an Indian medical center, researchers found that xerosis was the most common physiological skin change and pruritus was the most frequent complaint.
May 2026 in “Nature Communications” In this study, researchers identified that keloid fibroblasts respond to neurotransmitters from catecholaminergic nerves by producing bone matrix proteins, mediated by β1-adrenergic receptor activation, leading to fibro-osseous reprogramming; blocking this signaling in a rodent model prevented the development of keloid-like pathology.
176 citations
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June 2019 in “Cells” This review discusses dermal cell heterogeneity in wound healing and scar formation, highlighting the varied roles of different fibroblasts and the potential of skin substitutes without presenting new clinical results.
21 citations
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April 2019 in “Endocrinology and Metabolism Clinics of North America” This review discusses skin diseases in transgender patients receiving gender-affirming hormone therapy and procedures, highlighting unique conditions and the underdiagnosis that affects their quality of life and mental health.