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AKR1B10 enzyme may cause keloid scars and could be a treatment target.

This study identified two key epigenetic-related genes, HR and SMYD4, which may act as potential biomarkers in keloid disease, suggesting new therapeutic avenues for further research.

This review examines the histological features of keloid disease, its differentiation from similar skin conditions, and emphasizes gaps in current research while reporting no new clinical findings.

This review discusses genome-wide association studies in dermatology, noting that variants linked to risk for 10 skin complex diseases have been identified, with potential implications for diagnostics and management; it reports no new clinical results.

This article reviews the variations and risks associated with skin conditions in melanin-rich individuals, including assessment challenges and complications from common skin treatments, but presents no new research findings.

This article reviews Acne Keloidalis Nuchae and presents a successful treatment case using Homoeopathy, emphasizing the need for individualized treatment approaches, but reports no new clinical results.

Different races and genders have unique skin and hair issues, requiring specialized care and more research for effective treatment.

This narrative review explores contraindications for fractional CO2 laser treatment of aesthetic disorders, highlighting conditions such as pigmentary disorders, active skin conditions, photosensitivity, and recent isotretinoin use, emphasizing the importance of careful patient selection to minimize risks and enhance safety and effectiveness.

This review discusses botulinum toxin's experimental off-label uses in dermatology, highlighting promising results but emphasizing the need for more clinical trials to confirm efficacy and safety.

In this study of elderly patients at an Indian medical center, researchers found that xerosis was the most common physiological skin change and pruritus was the most frequent complaint.

E13 fetal mouse fibroblast vesicles may help reduce scarring.

In this study, researchers found that miR-3606-3p is significantly downregulated in skin fibrosis and correlates with disease severity, with its ability to inhibit key signaling pathways suggesting potential therapeutic applications for conditions like systemic sclerosis and keloids.

In this source, recent single-cell RNA-sequencing advances reveal significant transcriptional heterogeneity among skin fibroblasts, and the discussion focuses on the distinct subtypes' roles in skin homeostasis, repair, and their evolution in fibrotic diseases like keloid scars and cancer.

This review discusses skin diseases in transgender patients receiving gender-affirming hormone therapy and procedures, highlighting unique conditions and the underdiagnosis that affects their quality of life and mental health.

This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.

This issue of the Journal of Cosmetic Dermatology reviews several topics, including the use of radiofrequency in aesthetics and cannabinoids for skin diseases, but presents no new research findings.

This article reviews the literature on the off-label use of botulinum toxin for dermatological conditions, highlighting its potential effectiveness in treating rosacea, anal fissures, Raynaud phenomenon, hypertrophic scars, keloids, and hidradenitis suppurativa.

In this study, researchers observed a strong association between keloid scars and atopic dermatitis, suggesting a link between keloids and signs of atopy in a diverse patient population.

This article reviews the most common skin diseases worldwide and reports no new clinical findings.

This article discusses prevalent skin diseases in children, including alopecia areata, and reports no new clinical results; it outlines conditions and treatment options without presenting original data.

The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.

This study reports that four Indian patients with acne keloidalis nuchae also exhibited acanthosis nigricans, suggesting a potential link to metabolic syndrome, though further research is needed to confirm this association.

This study found that haploinsufficiency of SPINK5 can lead to Netherton syndrome when a single null mutation combines with homozygous G1258A polymorphisms, suggesting it acts as a genuine mutation affecting LEKTI function.

This abstract provides issue information for the Dermatologic Therapy journal's November/December 2016 edition and offers no new study results.

This study reviews the therapeutic applications and evidence around punch-based dermatologic techniques, highlighting their varying effectiveness and precision across different conditions, but emphasizes the need for further standardized research.

The document concludes that various skin conditions have specific characteristics and treatments, and highlights the importance of vitamin D in managing these dermatological issues.

This study found that inhibiting the HEDGEHOG-GLI1 pathway could reduce keloid size and gene expression, suggesting it as a potential therapeutic target for keloid pathogenesis.

This study identified m6A-related genes, particularly IGF2BP3, as significantly up-regulated in keloid patients, potentially implicating them in the condition's molecular mechanisms and suggesting targets for therapy.

In this review, the authors summarize classical and recent insights into the biology and treatment of hypertrophic scars and keloids, concluding that while understanding and strategies have advanced, effective prevention and treatments remain unsatisfactory.

This review explores fibroblast heterogeneity in the mammalian dermis and suggests potential therapeutic applications by targeting fibroblast subtypes, but reports no new experimental results.