March 2025 in “Jurnal Farmamedika (Pharmamedica Journal)” In this study, Indonesian spices were screened in silico for their potential to inhibit MMP9 and TNFα, which are involved in chronic diabetic wounds, and procyanidin was identified as the most promising therapeutic candidate due to its low binding energy to both proteins.
May 2024 in “EAS Journal of Pharmacy and Pharmacology” In this study, researchers used molecular docking to show that compounds from pomegranate peels, such as apigenin, luteolin, and taxifolin, effectively inhibit the enzyme 5α-reductase, suggesting potential anti-alopecic properties.
In this study using a virtual screening approach, eriocitrin and silymarin were identified as potent flavonoid compounds that strongly and stably interacted with 5α-reductase type II, suggesting potential development as novel treatments for androgenic alopecia.
December 2022 in “Journal of Natural Remedies” This study found that compounds extracted from Cucurbita maxima seeds at 50 °C for 2 hours demonstrated significant binding affinities against breast cancer-related proteins, suggesting potential anticancer activity needing further in vitro and in vivo evaluation.
August 2022 in “Indonesian Journal of Medical Chemistry and Bioinformatics” This in-silico study identified several compounds as potential Vitamin D Receptor agonists, with Dolichosterone showing the strongest binding energy.
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the ethyl acetate extract of Semecarpus anacardium leaves demonstrated cytotoxicity against MCF-7 cancer cells and induced apoptosis, suggesting potential as a cancer treatment with fewer side effects.
This paper discusses the potential benefits and preparation process of tofu made from almonds and sunflower seeds, but reports no new clinical results, and suggests further research is needed.
In this study, researchers found that the bioactive lipid sphingosine 1-phosphate and its receptor, S1PR3, are essential for regulating mechanical pain sensitivity in mice.
April 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that polygonum multiflorum may treat androgenic alopecia by mediating the PI3K/Akt pathway to regulate apoptosis, inhibit inflammation and oxidative stress, and induce melanin production.
March 2022 in “Research Square (Research Square)” This study found that certain bioactive mushroom metabolites may inhibit the enzyme SRD5A2 more effectively than finasteride in computational models, suggesting potential for further research in treating androgenic alopecia.
4 citations
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February 2018 in “Jurnal teknologi” This study found that Kaempferia galanga ethanolic extract has potential as an antifungal agent in an oil-in-water cream formulation, exhibiting stable physicochemical properties in laboratory tests.
January 2019 in “Applied Organometallic Chemistry” The compound (NH4)2Mn0.17Cu0.83Cl4.2H₂O has a specific structure, shows weak magnetism at low temperatures, and undergoes phase changes at high temperatures.
172 citations
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May 2018 in “Nature” Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
36 citations
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September 2015 in “Forensic Science International: Genetics” This study found that specific DNA variants in the TCHH, WNT10A, and FRAS1 genes are associated with predicting straight hair in Europeans, showing high sensitivity but low specificity, especially using a neural networks approach.
3 citations
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September 2019 in “Journal of Orthodontics” In this study, a 13-year-old boy developed temporary pressure alopecia from wearing orthodontic headgear, which resolved after discontinuation, highlighting a rare side effect that can affect psychosocial wellbeing.
January 2017 in “Research Portal (King's College London)” This paper analyzes Hilary Mantel's memoir and suggests that conflicts between her bodily experiences and psychological identifications affected her acceptance of a female gender identity, influencing her experience of endometriosis.
9 citations
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December 2014 in “Daehan miyong hakoeji” Peppermint oil promotes hair growth and fights bacteria better than minoxidil.
6 citations
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January 2013 in “Korean Journal of Pharmacognosy” Wheat bran can boost hair growth by affecting cell cycle proteins and signaling pathways.
6 citations
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June 2011 in “Daehan miyong hakoeji” The researchers reported that shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens showed potential as safe and effective natural ingredients for scalp care and scaling due to their antioxidative and antimicrobial properties.
5 citations
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January 2010 in “The Journal of Internal Korean Medicine” This study suggests that Lygodium japonicum may reduce cell damage and tissue proliferation in a rat model of benign prostatic hyperplasia, indicating potential as a treatment.
4 citations
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January 2017 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” Gagamhwajung-hwan may effectively treat severe alopecia areata.
4 citations
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April 2015 in “대한비뇨기종양학회지” This study concluded that packaging tamsulosin and finasteride together for co-administration in patients with benign prostatic hyperplasia improves medication adherence compared to packaging each drug separately.
4 citations
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February 1995 in “Journal of Clinical Dermatology” This study observed an increasing trend of young patients with androgenetic alopecia visiting dermatologists, with genetic factors and abnormal androgen metabolism in the scalp contributing to its development.
3 citations
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January 2019 in “The Journal of Pediatrics of Korean Medicine” Herbal medicine helped regrow hair in a child with alopecia areata.
3 citations
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December 2014 in “Daehan miyong hakoeji” 3 citations
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September 2011 in “Daehan miyong hakoeji” This study found that Dansam-Samultang promoted hair growth and increased follicle number and depth in C57BL/6 mice, with effects similar to those of minoxidil.
2 citations
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January 2017 in “Journal of the Korea Academia-Industrial cooperation Society” Saponin astragaloside from Astragalus membranaceus Bunge effectively enhances eyebrow growth.
2 citations
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March 2015 in “Daehan miyong hakoeji” 2 citations
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January 2015 in “Jounal of The Korean Society of cosmetology” This study found that combined intake of enzyme food and collagen was more effective than either alone in improving scalp hair properties in middle-aged women.
2 citations
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January 2011 in “The Korea Journal of Herbology” In this study, the herbal hair tonic and natural food treatment in C57BL/6 mice were associated with increased hair density and thickness compared to controls, suggesting potential hair growth benefits.