research Blood Plasma Levels of Heart Disease Biomarker Cardiac Troponin I Are Significantly Increased in Alopecia Areata Affected Individuals
People with alopecia areata have higher levels of a heart disease marker in their blood.
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research Inositol Versus Metformin Administration in Polycystic Ovarian Disease Patients
Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.
research To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease
The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.
research Autoimmunity and Autoimmune Co-Morbidities in Psoriasis
Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.
research Micro-Regional Transcriptome Reveals Local Dermal-Epidermal Intercorrelation in Atopic Dermatitis
Atopic dermatitis shows a link between skin layers in inflammation, detectable with detailed gene analysis.
research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
research Immunopathology and Immunotherapy of Inflammatory Skin Diseases
New targeted immunotherapies are improving treatment for inflammatory skin diseases.
research Identification of an Osteopontin-Derived Peptide That Binds Neuropilin-1 and Activates Vascular Cells
FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
research Baricitinib: From Rheumatoid Arthritis to COVID-19
Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
research Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs
Current treatments for Alopecia Areata have mixed success, and there's a need for better, more accessible options and support for affected individuals.
research Screening for Associated Autoimmune Disorders in Polish Patients with Addison’s Disease
research Construction of the Coexpression Network Involved in the Pathogenesis of Thyroid Eye Disease via Bioinformatics Analysis
Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research The Role of R-Spondins and Their Receptors in Bone Metabolism
R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
research Cell Death in Skin Function, Inflammation, and Disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research The Effect of DNMTs and MBPs on Hypomethylation in Systemic Lupus Erythematosus
Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.
research Skin, Mucosa and Nail Findings in Hospitalized Pediatric Patients With COVID-19
Many hospitalized children with COVID-19 had skin, mouth, or nail changes, with skin rashes being common.
research Measurement of Steroid Hormones by Liquid Chromatography-Tandem Mass Spectrometry with Small Amounts of Hair
A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Drug-Induced Skin, Nail, and Hair Disorders
Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
research Studies on the Proteome of Human Hair: Identification of Histones and Deamidated Keratins
Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
research Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice
Only skin melanocytes, not other types, can color hair in mice.
research COVID-19 and Autoimmunity in Dermatology: A Moroccan Case Series and Literature Review
COVID-19 can lead to different skin symptoms and might trigger autoimmune diseases in genetically susceptible people.
research Telomere Dysfunction Impairs Epidermal Stem Cell Specification and Differentiation by Disrupting BMP/pSmad/P63 Signaling
Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
research Histomorphology and Chemical Constituents of Interdigital Gland of Vembur Sheep, Ovis Aries
The interdigital gland of Vembur sheep shows sex-based differences in size and chemical makeup, possibly affecting communication and disease protection.
research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Wnt/β-Catenin Pathway in Tissue Injury: Roles in Pathology and Therapeutic Opportunities for Regeneration
The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
research Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia Through Overgrowth of Lactobacillus Murinus in Mice
An imbalanced gut and lack of biotin can cause hair loss in mice.
research Vitiligo
Vitiligo causes white skin patches and is linked to autoimmune issues.