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Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Cathepsin L is essential for normal hair growth and development.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that proper diagnosis and a combination of medical, hair-care, and surgical treatments are important for managing alopecia in black women.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Treatments for melanin disorders exist, but more effective options needed.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Tight hairstyles and chemical relaxers can cause hair loss known as traction alopecia.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.

Celiac disease can cause skin problems that may get better with a gluten-free diet.