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Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Finasteride effectively blocks enzyme causing male pattern baldness.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.

Finasteride may help some male chronic pelvic pain patients, but more research needed.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.