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Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Oral tofacitinib may effectively treat hair loss in children with alopecia areata.

Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

Male hormones worsen kidney transplant damage, but blocking them helps.

Platelet-rich plasma might help with skin aging, ulcers, and hair loss, but more research is needed to prove its effectiveness and safety.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Reflectance confocal microscopy can help tell apart scarring from non-scarring hair loss.

The authors suggest systematically sourcing new product ideas from various internal and external places to improve innovation.

The Chinese version of the PCOS quality of life questionnaire is reliable and valid for Chinese-speaking women with PCOS.

Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.

Some topical treatments like corticosteroids and vitamin D analogues are effective for scalp psoriasis, but more long-term data is needed.

DNA phenotyping helps predict physical traits from DNA with varying accuracy and requires careful ethical and legal handling.

Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.

Hair absorbs molecules differently based on their size, charge, and love for water, and less at higher pH; this can help make better hair products.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.