This study suggests that pseudopelade may be an autonomous disease based on its distinctive clinical and histopathological features not present in other scarring alopecias.
74 citations
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June 2018 in “Cell death and disease” In this study, researchers found that depleting mtDNA in mice caused skin wrinkles and hair loss but restoring mitochondrial function reversed these effects, highlighting mtDNA's significant role in skin and hair health.
58 citations
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July 2018 in “Journal of Allergy and Clinical Immunology” Alopecia areata severity is linked to increased TH1 and TH2 activity.
46 citations
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December 2018 in “Biomedical Optics Express” In this study, researchers observed that Raman spectroscopy effectively differentiates basal cell carcinoma from normal skin structures by analyzing biochemical markers, suggesting its potential as a surgical guidance tool for cancer margin resection during Mohs surgery.
42 citations
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November 2018 in “Archives of dermatological research” Apremilast was not effective in treating moderate-to-severe alopecia areata.
31 citations
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January 2019 in “Journal of Cutaneous Medicine and Surgery” This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.
25 citations
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September 2018 in “Molecular Biology of the Cell” This study found that in mice lacking EGFR, elevated Wnt signaling disrupts hair follicle development by affecting cell proliferation and differentiation, revealing a critical role for EGFR in regulating these processes.
June 2024 in “ESMO Gastrointestinal Oncology” The BAYONET trial is a phase II study designed to assess the efficacy and safety of combining encorafenib, binimetinib, and cetuximab for patients with BRAF V600E-mutant metastatic colorectal cancer that is resistant to encorafenib plus cetuximab; results are not yet reported.
January 2024 in “International Journal of Biological and Environmental Investigations” This study developed and validated a reliable RP-HPLC method for accurately quantifying dutasteride in pharmaceutical formulations and bulk pharmaceuticals using a Shiseido C18 analytical column, demonstrating precision, accuracy, and sensitivity across a concentration range of 10 to 22 ppm.
September 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study at Sree Ramakrishna Medical College in Tamil Nadu found that young females experiencing hair loss also report disturbed sleep, depression, and irritability, suggesting a need for increased awareness about health, nutrition, hair care, personal hygiene, and sleep among this population.
June 2023 in “Research Square (Research Square)” This study demonstrated that dietary cupric citrate improved growth performance and nutrient utilization in broilers, while also altering their intestinal microbiota and increasing the pH in the duodenum and jejunum.
July 2022 in “Research Square (Research Square)” This study found that hair testosterone concentrations show some consistency over time, but factors like hair washing and individual growth rates influence these levels, suggesting the need for careful sampling and analysis adjustments.
103 citations
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March 2015 in “Nature Communications” This study identified a genetic locus associated with idiopathic scoliosis in females, which might influence spinal gene expression and was previously linked to protection from early-onset alopecia.
18 citations
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January 1990 in “Journal of The American Academy of Dermatology” This study found that dexamethasone effectively suppressed DHEAS levels in women with elevated levels using much lower doses than previously thought, without significant adverse effects.
7 citations
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March 2023 in “Frontiers in Veterinary Science” This study found that camelina oil supplementation was comparable to flaxseed and canola oil in supporting skin and coat health and managing inflammation in dogs over 16 weeks.
2 citations
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January 2023 in “Curēus” In this study, low-dose naltrexone significantly reduced erythema in patients with frontal fibrosing alopecia and lichen planopilaris after one year, but no significant improvements were seen in other symptoms.
This case study reports the first known instance of lichen planopilaris being associated with multiple autoimmune syndrome in a woman with hypothyroidism and Crohn's disease.
June 2020 in “IP Indian journal of clinical and experimental dermatology” This observational study reported that primary ageing dermatoses were more common than non-ageing dermatoses among elderly patients, especially among those with pre-existing skin conditions.
39 citations
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January 2009 in “Journal of Ovarian Research” This study found moderate to poor agreement among observers assessing ultrasonographic features of polycystic ovaries, suggesting the need for standardized training modules to improve consistency.
2 citations
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March 2024 in “International Journal of experimental research and review” This study found that more than 14% of idiopathic recurrent early pregnancy loss cases were associated with chromosomal heteromorphisms, predominantly 9qh+, suggesting a genetic component in these unexplained cases.
2 citations
,
June 2023 in “Journal of clinical medicine” This review found that both oral and topical soy-based products showed positive effects on various skin-related outcomes, including aging signs and skin barrier function, but topical applications were more likely to improve skin barrier status compared to oral supplementation.
1 citations
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November 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” This study in Pudukottai district found that among 5870 individuals attending rural health camps, 1468 had skin complaints, with non-infectious conditions like eczema being most common, followed by fungal, bacterial, and arthropod infections.
1 citations
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August 2013 in “kufa journal for nursing sciences” This study assessed the nutritional status of elderly residents in a Baghdad nursing home, finding many are overweight with issues like easy hair loss and inadequate vitamin and mineral intake.
April 2026 in “Amino Acids” This study reviews prior research using transgenic K6/ODC mice and demonstrates that elevated polyamines in epithelial cells contribute significantly to skin tumor development and progression by stimulating proliferation, altering cell signaling and chromatin remodeling, and affecting immune functionality, amongst other mechanisms.
January 1981 in “The Journal of Toxicological Sciences” In this study, beagle dogs treated with hydrocortisone 17-butyrate 21-propionate ointment showed various toxic effects, including acne-like skin changes and organ atrophy, which returned to normal after a recovery period.
89 citations
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May 1999 in “Pediatric Dermatology” This article reviews the treatment options for tinea capitis, suggesting that itraconazole, terbinafine, and fluconazole are effective and safe alternatives to griseofulvin but reports no new clinical results.
54 citations
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March 2012 in “International Journal of Andrology” This study found that prenatal exposure to certain pesticides may lead to earlier breast development in girls, potentially associated with higher androgen levels.
14 citations
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December 1998 in “The Journal of Clinical Endocrinology and Metabolism” This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.
8 citations
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January 1996 in “Gynecological Endocrinology” This review evaluates therapies for hyperandrogenism, highlighting cyproterone acetate as the preferred treatment due to its potency and tolerability in managing symptoms in women.
8 citations
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October 1979 in “PubMed” In this study, jute-batching oil did not cause cancer in mice, but it shortened the time to tumour development when combined with a known carcinogen, indicating potential cancer-promoting activity.