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KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.

This study found that TRH modulates specific keratins in human scalp tissue, suggesting its potential influence on hair growth and the need for further exploration of neuroendocrine controls in keratin expression.

This study found that Magra sheep with high-luster wool exhibited significantly higher expression of keratin genes, suggesting that increased keratin protein levels may be crucial for wool luster.

This study found that mitochondrial oxidative phosphorylation in epithelial cells is necessary for proper enamel formation and odontoblast differentiation in developing incisor teeth in K320E-Twinkle Epi mice.

This review describes the unique pharmacological profile and clinical applications of pegylated liposomal doxorubicin, emphasizing its role in Kaposi's sarcoma and recurrent ovarian cancer, but reports no new clinical results.

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.

Keratins are crucial for cell structure, growth, and disease risk.

This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.

This review discusses keratin disorders and potential RNA interference therapeutics, reporting no new clinical findings but highlighting the promise of siRNA for future treatments.

This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.

This review discusses the features of regulatory T cells and the modulation of Foxp3, emphasizing post-translational modifications' impact on Treg function but reports no new clinical results.

In this study, researchers found that depleting mtDNA in mice caused skin wrinkles and hair loss but restoring mitochondrial function reversed these effects, highlighting mtDNA's significant role in skin and hair health.

This study found that the creation of hair follicle lumens in mice is driven by the outward migration of keratin 79-positive cells, suggesting a novel mechanism for generating hollow cores in hair follicles.

This study used proteomics to identify various proteins in human hair, which may help develop novel biomarkers for hair health, disease, and aging.

This chapter reviews keratins in skin epithelia, including their roles in cellular function and disease, and reports no new experimental results.

This study found that mice lacking the Vitamin D receptor showed disrupted hair follicle cycling, which was partially restored with hedgehog signaling pathway activation, suggesting a role for this pathway in follicle regulation independent of vitamin D.

This study found that the microRNA miR-22 is a key regulator of the hair cycle, influencing hair loss by promoting the transition from growth to rest phases and repressing keratinocyte differentiation.

This study found that while extracellular matrix components like hyaluronic acid promoted larger organoid formation, other matrix components hindered hair follicle germ assembly in an in vitro model.

This study used proteomic techniques to analyze human hair proteins, revealing keratin heterogeneity and identifying posttranslational modifications, such as cysteine trioxidation and methylation.

This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.

In this study, experimentally induced weight loss in merino sheep led to a decrease in wool fiber diameter and increased expression of certain high sulfur and glycine-tyrosine proteins, potentially impacting wool quality and industry preferences.

This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.

This review discusses how neuroendocrine pathways influence keratin regulation in human skin and hair follicles and suggests these pathways as potential targets for new treatments of skin disorders, but reports no clinical results.

This study's molecular dynamics simulations suggest that electrostatic interactions mainly stabilize peptide binding to human hair keratin, with the protein's dielectric constant significantly affecting free energy calculations.

This study found distinct differences in protein expression and wound healing pathways between Acomys cahirinus and Mus musculus, highlighting potential targets for reducing fibrotic response in mammals.

In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.

This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.

The researchers reported that keratin 33A is a structural protein specific to goat cashmere hair, with increased winter expression in high-cashmere-producing breeds.

This review discusses advancements in understanding hair cycle and inflammatory alopecias, proposing a standard classification and tiered treatment recommendations, but reports no clinical results.

This study found that hair with lower levels of keratin associated proteins reduced the foreign body response in mouse subcutaneous implant tests compared to hair with higher keratin levels.