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This study found that keratin K14 expression occurs early in epidermal cell differentiation, while a hair-specific keratin is expressed later in hair matrix cells, suggesting developmental divergence between the two cell types.

In this study, the researchers reported that the expression of keratin 14 in the skin and hair follicles of neonatal and juvenile rats differs from that observed in adults or human embryos.

This study reported that K14 expression patterns and keratin filament organization in human skin's hair follicles differ from those in the epidermis, indicating distinct differentiation programs.

This review discusses the role of miRNA/mRNA regulatory networks in skin development, epidermal homeostasis, and tissue remodeling, and suggests potential for miRNA-based therapies in treating skin conditions, but reports no new clinical results.

This study found that deleting FoxN1 in specific thymic epithelial cells disrupted the 3D thymic structure and led to age-dependent formation of 2D epithelial cysts, highlighting FoxN1's critical role in thymic morphogenesis.

This study found that TRH modulates specific keratins in human scalp tissue, suggesting its potential influence on hair growth and the need for further exploration of neuroendocrine controls in keratin expression.

In this study, expressing human K16 in the epidermis of K14 null mice prevented early skin blistering but led to age-related anomalies, indicating K16 and K14 have distinct roles despite their sequence similarity.

This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.

This study found that specialized nipple epidermis in mice is maintained by the repression of TGFβ signaling through estrogen, which highlights the role of hormonal regulation in epidermal maintenance.

This study suggests that hemoglobin α expression in the epidermis is induced by oxidative stress and may function as an antioxidant, contributing to skin barrier function.

This study suggests that hepatocyte growth factor (HGF) may play a role in hair follicle neogenesis and that an HGF mimetic could enhance skin substitute development.

This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.

This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.

This study found that prolactin is a key regulator of keratin expression in human hair follicles, enhancing specific keratin types and influencing epithelial stem cell-associated keratins.

This article reviews the genetic and protein interactions involved in hair growth, highlighting regulatory sequences, expression patterns, and potential genetic modifications, but presents no new experimental findings.

This study identified key mRNAs and lncRNAs, along with related pathways, that play potentially important roles in hair follicle development and cycling in cashmere goats.

This study found that ALKBH5 plays a critical role in wound re-epithelialization by enhancing the stability of PELI2 mRNA, and its absence delays wound healing. Supplementation with PELI2 can partially rescue this delay, pointing to potential new therapies for stubborn wounds.

In this study, constitutive expression of Del1 in mice did not affect wound healing but was associated with increased hair growth following anagen induction.

This study found that lymphatic vessels promote hair follicle growth in mice, suggesting new therapeutic strategies for hair loss treatments.

This study found that type II diabetes inhibited hair follicle regeneration and skin cell proliferation in mice, potentially explaining reduced skin renewal and chronic wound formation in diabetes.

This study found that keratin 15 lacks the ability to sequester YAP1 in keratinocytes effectively, unlike keratin 14, and suggests that a higher K15:K14 ratio may promote a progenitor state and inhibit differentiation in epidermal keratinocytes.

This study demonstrated that hair follicle bulge stem cells can form epidermis in a tissue-engineered skin model, highlighting the significance of K5/K17 filaments in slow-cycling stem cell subsets.

In this study, transgenic mice altered to express a Clim-inhibiting molecule under a keratin promoter showed corneal degradation and hair follicle failure, highlighting Clim proteins' role in maintaining these tissues.

S100A8 and S100A9 proteins help form hair shafts during growth.

Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.

In this study, transgenic mice expressing a mutant K6 gene developed progressive scarring alopecia and keratosis, suggesting they may model a new keratin disorder.

This study found that patients with active severe alopecia areata exhibited decreased CD200 expression on T and B lymphocytes, which may be linked to an imbalance in Th1/Th2 immune equilibrium.

The study found that over-expressing ornithine decarboxylase in the outer root sheath of the hair follicle in mice increases UVB-induced tumor growth and invasive squamous cell carcinoma compared to inter-follicular epidermal keratinocytes.

This study characterized a new human keratin, hK6irs1, specifically found in the inner root sheath of hair follicles, which suggests its role in the structural integrity and guidance of growing hair shafts.

This study found a significant association between reduced FGF13 levels and X-linked congenital generalized hypertrichosis, suggesting FGF13's potential role in hair follicle growth and the hair cycle.