research Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives
A new method efficiently modifies alkenes to create useful medicinal compounds.
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research Ginseng Phytochemicals as Therapeutics in Oncology: Recent Perspectives
Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
research Bariatric Surgery for Spontaneous Ovulation in Women with Polycystic Ovary Syndrome: The BAMBINI Multicentre, Open-Label, Randomised Controlled Trial
Bariatric surgery improves ovulation rates in women with PCOS and obesity better than medical therapy.
research The Persistent Effects of 5α-Reductase Inhibitors Used in the Treatment of Androgenic Alopecia on Men’s Health
Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.
research Phytochemicals as Emerging Therapeutic Agents for Alopecia Treatment
Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.
research Fungal Skin Infections in Children: Focus on Tinea Capitis
Accurate diagnosis and proper treatment are crucial for managing fungal skin infections in children.
research Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome
Follow the latest international guidelines to assess and manage Polycystic Ovary Syndrome effectively.
research Alopecia Universalis in a Dog with Testicular Neoplasia
A combination of ciclosporin and ketoconazole can effectively treat severe hair loss in dogs.
research Postherpetic Poliosis
A man's chest hair turned white after a shingles infection, possibly due to virus-damaged pigment cells.
research Effectiveness of Combined Oral Minoxidil and Finasteride in Male Androgenetic Alopecia: A Retrospective Service Evaluation
Combined oral minoxidil and finasteride significantly improve hair density in men with male pattern baldness.
research Active Compounds With Medicinal Potential Found in Maxillariinae Benth. Representatives: A Review
Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Mammographies
Mammograms are important for detecting breast cancer early.
research Therapeutic Potential of Extracellular Vesicles (Exosomes) Derived From Platelet-Rich Plasma: A Literature Review
Exosomes from platelet-rich plasma may help heal wounds but need more research for hair growth and skin use.
research Preparation of 4-Aryl-2-Trifluoromethylbenzonitrile Derivatives as Androgen Receptor Antagonists for Topical Suppression of Sebum Production
Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
research Core-Shell Nanocarriers Based on PEGylated Hydrophobic Hyperbranched Polyesters
The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.
research Hyperbranched Glycerol-Based Core-Amphiphilic Branched Shell Nanotransporters for Dermal Drug Delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
research Prevalence and Predictors of Persistent Post-Covid-19 Symptoms
Some people still have COVID-19 symptoms after 90 days, especially older patients and those with severe initial symptoms, but most return to normal.
research A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis
Inhibiting ODC can prevent UV-induced skin cancer.
research An Exclusive Review on Menstrual Problems
Eating better, exercising, staying clean during periods, and learning about health can help reduce menstrual problems and improve life quality.
research Clomiphene Citrate as Nanomedicine Assistance in Ovulatory Disorders and Its Hyphenated Techniques
Nanotechnology improves Clomiphene citrate's effectiveness and reduces side effects for treating ovulatory disorders.
research Long-Acting Microneedle Formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
research Dilemma of Postoperative Scarring in Cleft Lip and Palate: A Narrative Review
Scarring after cleft lip and palate surgery is a major issue, and the review looks at ways to manage it.
research Alefacept for Severe Alopecia Areata: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial
Alefacept does not effectively treat severe alopecia areata.
research Identification of the Causative Dermatophyte of Tinea Capitis in Children Attending Mbarara Regional Referral Hospital in Uganda by PCR-ELISA and Comparison with Conventional Mycological Diagnostic Methods
PCR-ELISA is better for identifying the fungus causing scalp infections in Ugandan children than traditional methods.
research Larvicidal Potential, Antimicrobial Properties and Molecular Docking Analysis of Egyptian Mint (Mentha Rotundifolia) Against Culex Pipiens L. (Diptera: Culicidae) and Midgut-Borne Staphylococcus Aureus
Egyptian Mint effectively kills mosquito larvae and inhibits certain bacteria.
research Evaluating the Efficacy of Different Platelet-Rich Plasma Regimens for Management of Androgenetic Alopecia: A Single-Center, Blinded, Randomized Clinical Trial
PRP injections effectively treat hair loss, with positive results in both monthly and every three months treatments.
research Oral Low-Dose Naltrexone in the Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: An Uncontrolled Open-Label Prospective Study
Low-dose naltrexone may help reduce redness in certain scalp conditions.
research Factors Driving Unique Urination Phenotypes of Male and Female 9-Week-Old C57BL/6J Mice
Testosterone significantly affects urination differences between male and female mice.