July 2008 in “British Journal of Dermatology” Cyclosporin doesn't stop hair loss.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
90 citations,
April 2013 in “Dermatology online journal” Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
Vitamin D is crucial for skin health and managing skin diseases.
12 citations,
December 2010 in “Journal of thoracic oncology” New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
2 citations,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
1 citations,
July 2016 in “Elsevier eBooks” Understanding skin structure and development helps diagnose and treat skin disorders.
658 citations,
June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
222 citations,
October 2014 in “Annual Review of Pharmacology and Toxicology” Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
106 citations,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
85 citations,
May 2019 in “Journal of neuroendocrinology” The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
35 citations,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
24 citations,
May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
21 citations,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
2 citations,
January 2014 in “Springer eBooks” The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
December 2021 in “Benha Journal of Applied Sciences” Higher Claudin 3 levels in the blood are linked to more severe alopecia areata.
Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
1 citations,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
28 citations,
January 2016 in “Vitamins and hormones” Thymosin β4 helps improve skin healing and reduce scarring.
480 citations,
August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
55 citations,
March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
26 citations,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
March 2013 in “Actas Dermo-Sifiliográficas” The document concludes that there have been significant improvements in diagnosing and treating skin diseases, including melanoma, with new techniques and therapies.