research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
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research Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth
Activating TRPV3 stops human hair growth.
research Control of Hair Follicle Cell Fate by Underlying Mesenchyme Through a CSL–Wnt5a–FoxN1 Regulatory Axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research Congenital Adrenal Hyperplasia: A Comprehensive Review
The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
research The Spectrum of Scarring in Craniofacial Wound Repair
Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Realizing the Therapeutic Potential of Neuroactive Steroid Modulators of the GABAA Receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Hutchinson-Gilford Progeria Syndrome: Current Status and Prospects for Gene Therapy Treatment
Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.
research FOXN1 Deficiency: From the Discovery to Novel Therapeutic Approaches
New treatments for immune disorders caused by FOXN1 deficiency are promising.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Fibromodulin Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors During Adult Mouse Skin Wound Healing
Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
research MicroRNAs in the Skin: Role in Development, Homeostasis, and Regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Applications and Risks of Nanomaterials Used in Regenerative Medicine, Delivery Systems, Theranostics, and Therapy
Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
research Differential Expression of Stem Cell Markers in Human Follicular Bulge and Interfollicular Epidermal Compartments
Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
research Cholesterol Homeostasis: Links to Hair Follicle Biology and Hair Disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
research The Role of R-Spondins and Their Receptors in Bone Metabolism
R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
research Potassium Channel Openers: Therapeutic Potential in Cardiology and Medicine
Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Mechanisms Underlying Select Chemotherapeutic-Agent-Induced Neuroinflammation and Subsequent Neurodegeneration
Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.
research Secondary Cicatricial and Other Permanent Alopecias
The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research Promoting Axonal Regeneration Through Exosomes: An Update of Recent Findings on Exosomal PTEN and mTOR Modifiers
Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
research Wnt Signaling Activation: Targets and Therapeutic Opportunities for Stem Cell Therapy and Regenerative Medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.