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Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

The model can effectively test gene functions and drug responses in human skin.

Finasteride helps female-pattern hair loss.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.

Low dose methotrexate does not increase hair fall and may reduce it.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Some medicinal plants can help heal wounds and may lead to new treatments.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Different types of stem cells and their environments are key to skin repair and maintenance.

Tofacitinib may help treat severe hair loss, but more research is needed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Alopecia areata treatment varies, with no optimal method established yet.