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Four-amino acid part makes enzyme sensitive to finasteride.

A new gene, JMJD1C, may affect testosterone levels in men.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Neurosteroids show promise for treating epilepsy and more research is needed.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

New alopecia treatments aim for better results and fewer side effects.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Finasteride reduces gambling symptoms in Parkinson's patients.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Probe detects finasteride with high selectivity and low detection limit.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.