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Keloids significantly reduce quality of life, and treating symptoms should be prioritized.

HSD11b1 affects skin nerves and increases non-histaminergic itch.

CP-690,550 significantly reduced itching in patients with moderate-to-severe plaque psoriasis.

Botulinum toxin type A reduces itch and inflammation from histamine and may help treat certain skin conditions and hair loss.

Itch is a common symptom in patients with chronic venous insufficiency, often accompanied by burning and pain.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

Consider DRIF and perform skin biopsies for persistent papular rashes.

ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.

H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.

Hair casts are harmless but can be mistaken for head lice.

Henna ointment may help reduce itching and improve wound healing in patients with epidermolysis bullosa.

Zinc pyrithione in shampoo or rinse reduces dandruff and itching.

Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.

The top research priorities for congenital ichthyosis include long-term side effects of oral retinoids, best topical treatments, and treatments for itch and hair loss.

Itch is a common symptom in patients with chronic venous insufficiency, often worsening with standing or sitting and occurring mostly in the evening or at night.

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

Treating scalp issues in hair-pulling disorder helps hair regrow and reduces itch.

Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

μ-opiate receptors in skin cells may affect skin health and healing.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

Patients with cutaneous lupus are most concerned about self-consciousness, physical symptoms, and disease progression.

A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.

People with TED often have low B12 levels and might benefit from B12 supplements.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.

Patients with ichthyosis often experience symptoms similar to psoriasis and atopic dermatitis, suggesting that targeted therapies could improve their condition.

People with telogen effluvium and scalp discomfort might have low vitamin B12 and could benefit from B12 supplements.

Patients with nonmelanoma skin cancers are most bothered by fear of progression, appearance concerns, and having cancer.

Iron deficiency anemia can cause itching, which often improves with iron supplements.