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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Compound 4 is a promising treatment for hair loss with low toxicity.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Muscles can make their own androgens, which may help muscle growth.

sPLA2-X is crucial for normal hair growth and follicle health.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.

Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

PRP is effective for treating hair loss, especially with other treatments.

Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.

Purple sweet potato leaf extracts can help treat hair loss and fungal infections.

Finasteride may lower cholesterol and slow heart disease progression.

Some medications might contribute to male infertility, with finasteride showing a high number of reports.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Teak leaf extract contains compounds that could help treat hair loss.

Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.

Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.