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New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

Gene differences may affect baldness treatment response in Korean men.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Goat skin changes with the seasons due to genes affected by daylight and hormones.

Finasteride use may cause sexual dysfunction; more research needed.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Cyclosporin A promotes hair cell growth and affects protein kinase C levels.

The document discusses male and female pattern hair loss, its diagnosis methods, FDA-approved treatments like finasteride and minoxidil, their side effects, and the role of lifestyle changes.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Both drugs lower DHT levels, with GI198745 being more effective.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Testosterone may slow down wound healing and increase inflammation.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.