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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Finasteride 5-mg oral disintegrating tablets and standard tablets are bioequivalent in healthy adult male Han Chinese volunteers.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

Terazosin and finasteride together cause no major issues.

Finasteride causes sperm production decrease in Mesocricetus auratus.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

PGD2 stops hair growth and is higher in bald men with AGA.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Hair loss needs more research for better treatments.

Male pattern baldness involves genetics, hormones, and needs better treatments.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Four-amino acid part makes enzyme sensitive to finasteride.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Some common medications can harm male fertility, but many effects can be reversed.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Applying a specific inhibitor lightens skin and hair color.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.