Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reported that oral isotretinoin can be an effective and safe treatment for acne vulgaris when used at the appropriate dosage, offering a low-complication option.

This study found that isotretinoin therapy for acne vulgaris typically causes mild mucocutaneous adverse events, which are reversible and vary individually.

This article discusses the features and increasing prevalence of frontal fibrosing alopecia, a type of scarring hair loss, and reports no new clinical results.

This systematic review found that hair loss was more frequently observed in acne patients on isotretinoin doses ≥0.5 mg/kg/d compared to those on lower doses, suggesting dose-dependent effects.

In this study, patients with facial papules due to Lichen planopilaris showed no improvement with treatments for frontal fibrosing alopecia or scalp Lichen planopilaris.

This retrospective study found that hair loss occurred in some isotretinoin patients, with those experiencing hair loss being older and having longer treatment durations and higher doses compared to controls.

This study found that adding 10 mg/day of biotin to isotretinoin treatment for acne improved hair growth and maintained skin hydration, potentially reducing isotretinoin's mucocutaneous side effects.

Isotretinoin may cause hair loss, especially in women and young adults.

In this study, using a combination of topical minoxidil (2%) and isotretinoin (0.05%) gel led to complete hair regrowth in 83.3% of alopecia areata patients within six months, demonstrating effective and well-tolerated treatment results.

In this study, the authors suggest that patient safety with isotretinoin in Palestine can be improved by adapting pharmacy and medical practice protocols to better educate patients and ensure adherence to safety monitoring and laboratory ordering.

In this survey study, dermatologists in the Aseer region of Saudi Arabia generally exhibited good knowledge of isotretinoin's ocular side effects like dry eye and contact lens intolerance, but their practices varied regarding patient education and management of these effects.

This review discusses isotretinoin's effectiveness against severe acne vulgaris and its associated side effects, including teratogenicity and hair loss, but it reports no new experimental results.

This case report describes an 18-month-old male with ichthyosis follicularis alopecia photophobia syndrome who experienced transient improvement in skin symptoms after oral isotretinoin treatment.

This study found that among young patients with acne vulgaris, combining a 675 nm red-light laser with isotretinoin led to more rapid and pronounced improvement in lesion severity compared to laser treatment alone, without adverse events.

This study identified several previously unrecognized adverse events linked to ISO, including serious conditions such as Dandy-Walker syndrome and suicidal ideation, suggesting that safety measures and drug labeling should be updated.

This article reviews the use of isotretinoin for acne treatment and its controversial association with depression and suicide, noting limited evidence for a direct link.

This article describes SAHA syndrome, which includes symptoms of nodulocystic or severe acne, female pattern hair loss, and hirsutism, but reports no new results.

In this study, researchers reviewed data on isotretinoin and concluded that delaying certain skin procedures like laser hair removal and chemical peels after isotretinoin treatment may not be necessary, though caution is advised for fully ablative treatments, and lower isotretinoin doses are recommended.

In this case study, the combination therapy of isotretinoin and rifampicin was reported to effectively improve symptoms in a 58-year-old female patient with folliculitis decalvans, suggesting this approach may warrant further investigation for treating this challenging condition.

In this study, isotretinoin treatment significantly increased p53 expression in the skin of acne vulgaris patients, correlating with reduced acne severity and suggesting mechanisms for sebum suppression and side effects.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

This study found that female isotretinoin users who also took oral contraceptives were more likely to experience elevated triglyceride or cholesterol levels.

Isotretinoin can raise CPK levels, so patients need monitoring, especially before surgery.

In this study, researchers found no association between the use of oral isotretinoin at a standard dose and the development of milia in patients with moderate-to-severe acne vulgaris.

This review highlights the broad range of adverse effects associated with isotretinoin in acne treatment and examines strategies such as dietary supplementation and adjusted dosing protocols to enhance patient tolerability while maintaining efficacy.

In this case report, an 11-year-old girl with dissecting cellulitis of the scalp showed an excellent response to oral isotretinoin after other treatments failed, highlighting the treatment challenges and need for awareness in managing this rare condition.

This review synthesizes information on isotretinoin’s systemic toxicity, emphasizing that its adverse effects, including mucocutaneous, hepatic, and musculoskeletal reactions, primarily reflect its pharmacodynamic actions and are generally manageable with individualized dosing and monitoring, though its teratogenicity remains a significant safety concern.

This review highlights that isotretinoin effectively treats acne by addressing its pathogenic mechanisms, although managing its teratogenic risk and side effects through structured monitoring is crucial for safe use.

This narrative review assesses evidence on the role of oral supplements in reducing common side effects caused by isotretinoin treatment for acne vulgaris, with the aim of providing guidance for enhancing treatment tolerability.

This study reviewed isotretinoin's effectiveness in treating moderate to severe acne and discussed the need to balance its robust treatment benefits with careful monitoring due to significant physiological and psychological side effects.