research Mechanism of Action of Isotretinoin
Isotretinoin effectively treats severe acne but can cause significant side effects like dry skin and hair loss.
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30-60 / 1000+ resultsresearch Ichthyosis Follicularis Alopecia and Photophobia Syndrome: Transient Improvement with Oral Isotretinoin
Oral isotretinoin temporarily improved skin symptoms in a child with IFAP syndrome.
research The Efficacy of Oral Isotretinoin Versus Cyproterone Compound in Female Patients With Acne and the Triad of Cutaneous Hyperandrogenism: A Randomized Clinical Trial
Oral isotretinoin and cyproterone compound are equally effective for treating acne in women with cutaneous hyperandrogenism.
research Isotretinoin Treatment Upregulates the Expression of P53 in the Skin and Sebaceous Glands of Patients with Acne Vulgaris
Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.
research Isotretinoin
Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.
research Elevation of Serum Triglyceride and Cholesterol Levels from Isotretinoin Therapy with Concomitant Oral Contraceptives
Taking oral contraceptives while on isotretinoin may increase the risk of high triglyceride and cholesterol levels.
research Creatine Phosphokinase Levels and Isotretinoin Therapy
Isotretinoin can raise CPK levels, so patients need monitoring, especially before surgery.
research Oral Isotretinoin Therapy and Milia Formation in Patients with Acne Vulgaris: A Prospective Study
Oral isotretinoin does not cause milia in acne patients.
research Isotretinoin-Induced Hair Growth in a Case of Hereditary Hypotrichosis Simplex of the Scalp: A Promising Therapeutic Approach
Isotretinoin may effectively treat hereditary hypotrichosis simplex, a rare hair loss condition.
research A Review of Isotretinoin in the Treatment of Frontal Fibrosing Alopecia
Isotretinoin can effectively reduce symptoms of frontal fibrosing alopecia.
research Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects
Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.
research Isotretinoin-Unresponsive Acne as a Sign of a Congenital Disorder: A Case of 21-Hydroxylase Deficiency
Acne not improved by usual treatments may indicate a genetic disorder.
research MTORC1 Activity Is Increased in the Skin of Acne Patients and Is Suppressed With Isotretinoin Treatment
Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.
research Isotretinoin Treatment Upregulates the Expression of P53 in the Skin and Sebaceous Glands of Patients With Acne Vulgaris
Isotretinoin treatment increases p53 levels in the skin, which may explain its effectiveness against acne.
research Folliculitis Decalvans: A Case Report of Satisfactory Recovery After Implementing Isotretinoin Therapy
Isotretinoin effectively treated a rare scalp condition, but careful drug monitoring and a dairy-free diet were important.
research Isotretinoin Treatment Upregulates the Expression of p53 in the Skin and Sebaceous Glands of Patients with Acne Vulgaris
Isotretinoin treatment increases p53 levels in the skin, which may explain its effectiveness against acne.
research Facial Hypertrichosis After Isotretinoin Therapy: Is It a Side Effect or Coincidence?
Isotretinoin may cause temporary, reversible facial hair growth in some women.
research Is the Effect Worth the Risk? The Most Common Complaints During Oral Isotretinoin Anti-Acne Therapy and Controversies Around Its Adverse Effects
Most patients on isotretinoin for acne experience mild, dose-related side effects, but the connection to depression or bowel disease is uncertain.
research Isotretinoin-Induced Gynecomastia
Isotretinoin can cause gynecomastia by lowering testosterone levels.
research Reply to 'Facial Papules in Frontal Fibrosing Alopecia: Good Response to Isotretinoin'
Isotretinoin at low doses effectively treats facial papules in frontal fibrosing alopecia.
research Potential of Delonix Polymeric Nanoparticles Containing Isotretinoin for Acne Treatment
Delonix polymeric nanoparticles with isotretinoin effectively treat acne by targeting hair follicles and reducing skin irritation.
research A Prospective Trial of the Effects of Isotretinoin on Quality of Life and Depressive Symptoms
Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
research Effectiveness of Conventional, Low-Dose, and Intermittent Oral Isotretinoin in the Treatment of Acne: A Randomized, Controlled Comparative Study
Low-dose isotretinoin is as effective as conventional doses for acne and has fewer side effects.
research Cerebral Ischemia Related to Isotretinoin; Venlafaxine-Induced Alopecia; Cognitive Dysfunction with Tolterodine; Retinal Artery Occlusion After Injection of Long-Acting Risperidone; Olanzapine-Induced Chylomicronemia Presenting as Pancreatitis; Metabolic Effects of the Atypical Antipsychotics – An Editorial; Another Drug-Induced Pancreatitis – This One Caused by a Tyrosine Kinase Inhibitor; Suicide Attempts Related to Antidepressant Medications
The conclusion is that healthcare professionals should report adverse drug reactions to improve medication safety and patient care.
research Treatment of Acne with Intermittent Isotretinoin: Cohort Study
Intermittent isotretinoin can cause various skin, hair, and nail changes.
research Use of Oral Isotretinoin in the Treatment of Frontal Fibrosing Alopecia: Case Series
Oral isotretinoína effectively stabilizes frontal fibrosing alopecia.
research Evaluating the Combined Efficacy of Oral Isotretinoin and Topical Tacrolimus Versus Oral Finasteride and Topical Tacrolimus in Frontal Fibrosing Alopecia: A Randomized Controlled Trial
Isotretinoin with tacrolimus may be more effective short-term for treating frontal fibrosing alopecia than finasteride with tacrolimus.
research Finasteride, Isotretinoin, and Serotonin Reuptake Inhibitors: A Study on Enduring Sexual Dysfunction
Some medications may cause lasting sexual dysfunction.
research Oral Isotretinoin as the Most Effective Treatment in Folliculitis Decalvans: A Retrospective Comparison of Different Treatment Regimens in 28 Patients
Oral isotretinoin is the most effective treatment for folliculitis decalvans.
research Oral Isotretinoin Combined with Topical Clobetasol 0.05% and Tacrolimus 0.1% for the Treatment of Frontal Fibrosing Alopecia: A Randomized Controlled Trial
Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.