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May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” The type 3 IP3 receptor is important for controlling hair loss and growth.
883 citations,
August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
10 citations,
June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
81 citations,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
109 citations,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
3 citations,
September 2019 in “Clinical and experimental dermatology” Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.
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August 2009 in “Experimental dermatology” Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
38 citations,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
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September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
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January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
8 citations,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
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March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
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February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
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August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
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August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
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September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
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January 1979 in “International review of cytology” Wool follicles are complex, involving interactions between different cell types and structures.
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September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
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January 2009 in “Dermato-endocrinology” ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
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September 2006 in “Pharmaceutical Research” No treatment fully prevents hair loss from chemotherapy yet.
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
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November 2000 in “Clinics in Dermatology” Most hair loss in children is caused by a few common conditions and is easy to diagnose, but rare types require careful evaluation.
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March 2012 in “Journal of Investigative Dermatology” Some thymic peptides can increase human hair growth, while others may inhibit it.
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November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
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July 2023 in “Journal of developmental biology” Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
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January 2015 in “Hair therapy & transplantation” Hair follicle stem cells could be used to treat the skin condition vitiligo.
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June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking CCR5 can prevent and improve hair loss in alopecia areata.
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September 2007 in “Journal of Heredity” FGF5 gene mutations cause long hair in domestic cats.