49 citations
,
January 2010 in “International Journal of Pediatric Endocrinology” This review covers the pathophysiology, diagnosis, and treatment of nonclassic congenital adrenal hyperplasia due to P450c21, but it reports no new clinical results.
48 citations
,
April 2015 in “PLOS ONE” In this study, hirsutism was found to have the most significant negative impact on health-related quality of life among Iranian women with polycystic ovary syndrome.
46 citations
,
June 1990 in “Archives of dermatology” In this study, combination therapy with 5% minoxidil and 0.5% anthralin showed some cosmetic improvement in 11% of patients with severe treatment-resistant alopecia areata, with hair regrowth starting by week 12.
44 citations
,
October 2009 in “Journal of the American Academy of Dermatology” This study reported that 1% bexarotene gel was well tolerated and possibly effective for inducing partial hair regrowth in alopecia areata, but more rigorous trials are needed to confirm its efficacy.
40 citations
,
September 2024 in “European Journal of Endocrinology” This study found that global PCOS prevalence in adolescents is 6.3% under new 2023 guideline criteria, compared to 9.8% using Rotterdam criteria; excluding PCOM may prevent over-diagnosis, while recognizing irregular cycles or hyperandrogenism helps avoid under-diagnosis by identifying at-risk individuals for further monitoring.
40 citations
,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” This article outlines management guidelines for androgenetic alopecia, highlighting that continued treatment with medications like finasteride or minoxidil typically halts progression and improves hair condition in most mild to moderate cases.
39 citations
,
June 2017 in “Scientific Reports” Different lab conditions and light treatment methods change how human skin cells respond to light therapy.
38 citations
,
June 2004 in “Human Reproduction” This review discusses the challenges of using surrogate variables versus primary clinical end-points in PCOS trials and reports no new research results; the authors suggest focusing future studies on primary outcomes.
37 citations
,
September 2002 in “Acta pædiatrica” In this study, a patient with cystic fibrosis developed iatrogenic Cushing's syndrome due to impaired clearance of budesonide from concurrent itraconazole use, highlighting the need for regular monitoring in such combination therapies.
36 citations
,
April 2016 in “Experimental Dermatology” This review discusses the challenges in selecting optical parameters for photobiomodulation studies on hair regrowth and wound healing, reporting no new clinical results and recommending more rigorous, standardized research approaches.
36 citations
,
June 1990 in “Archives of Dermatology” This study found that combination therapy with 5% minoxidil and 0.5% anthralin led to hair regrowth in some patients with severe treatment-resistant alopecia areata, but also caused mild to moderate irritant dermatitis in all participants.
35 citations
,
July 2015 in “Journal of Affective Disorders” This study found that women with polycystic ovary syndrome have significantly higher scores for affective temperaments and anxiety and depression than healthy controls, suggesting risk for depressive and anxiety disorders.
34 citations
,
July 2011 in “Journal of the European Academy of Dermatology and Venereology” This study identified distinct dermoscopic patterns associated with different types of scalp tumors, highlighting variability in lesions related to patient age, gender, and tumor thickness.
31 citations
,
October 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)” This meta-analysis found that the prevalence of PCOS among Iranian women varies by diagnostic criteria, with notable rates of associated complications like hirsutism, acne, and menstrual disorders.
29 citations
,
March 2015 in “Clinical Endocrinology” This study found that women with polycystic ovary syndrome in the UK show significant differences in phenotypic and metabolic characteristics based on ethnicity, age, and obesity, influencing management strategies.
26 citations
,
November 2011 in “Arquivos Brasileiros De Endocrinologia E Metabologia” This review highlights that hyperandrogenism is a crucial factor for diagnosing PCOS during adolescence, while traditional criteria like polycystic ovarian morphology may be misleading.
26 citations
,
June 2003 in “Obstetrics and gynecology clinics of North America” This review discusses the use of insulin-sensitizing agent metformin for treating PCOS in adolescents, noting potential benefits but emphasizing the need for more rigorous trials due to current study limitations.
24 citations
,
November 2016 in “Molecular Medicine Reports” This study found that women with acne resistant to conventional treatments had significantly higher levels of testosterone, DHEA‑S, prolactin, and LH, suggesting potential underlying hormonal disorders.
23 citations
,
April 1991 in “Journal of The American Academy of Dermatology” Minoxidil solution can cause skin irritation and allergies in some users.
21 citations
,
April 2011 in “Clinical Cosmetic and Investigational Dermatology” This review discusses treatments for acne of varying severity and hormonal influences but reports no new clinical results; it suggests specific therapies for different acne types and highlights considerations for female patients.
21 citations
,
July 2001 in “Clinics in dermatology” This review discusses the clinical use of nutraceuticals for skin aging in dermatological practices and reports no new clinical results.
20 citations
,
January 2016 in “Open Journal of Endocrine and Metabolic Diseases” This article discusses the prevalence, diagnosis, and treatment of polycystic ovary syndrome, emphasizing its early diagnosis and management due to potential reproductive and metabolic complications, but reports no new findings.
19 citations
,
July 2019 in “Biomedical Microdevices” This review discusses the safety and potential adverse events of microneedling as both a medical and consumer product, noting the need for further understanding; no new clinical results are presented.
19 citations
,
February 2018 in “International Journal of Endocrinology and Metabolism” This study found that the revised 43-item PCOSQ had better validity and reliability than the original version, although further studies are needed to assess its predictive efficacy.
18 citations
,
July 2018 in “Turk Pediatri Arsivi-turkish Archives of Pediatrics” This study reported that the most common skin diseases among children in the Erzincan region of Turkey were preventable conditions, like acne and warts, suggesting the need for enhanced health education and preventive care.
18 citations
,
April 2016 in “Endocrinology and Metabolism Clinics of North America” This review discusses the diagnostic challenges of PCOS in adolescents, noting that the persistence of hyperandrogenism and oligomenorrhea is required for diagnosis, while genetic studies suggest involvement of the hypothalamic-pituitary-ovarian axis.
18 citations
,
March 1984 in “BMJ” Minoxidil helps hair regrowth in alopecia, but more research needed.
17 citations
,
August 2021 in “Dermatologic surgery” This review found that microneedling is generally safe, with most adverse effects being minor and resolving quickly, though there is increased risk in patients with active infections, darker skin, or metal allergies.
16 citations
,
December 2020 in “International Journal of Clinical Practice” This study found that urticaria, psoriasis, and allergic/irritant contact dermatitis were more commonly diagnosed during the COVID-19 pandemic period, while acne and some other dermatological conditions decreased compared to before the pandemic.
16 citations
,
September 2018 in “Clinical Biochemistry” This paper discusses the link between polycystic ovarian syndrome (PCOS) and health issues like infertility and cardiovascular diseases, caused by both genetic and environmental factors, but reports no new clinical findings.