318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
182 citations,
November 2018 in “Cosmetics” Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.
135 citations,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
115 citations,
August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
107 citations,
April 2014 in “The Plant cell” The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.
96 citations,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
90 citations,
December 2007 in “Current Oncology” Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
59 citations,
August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
53 citations,
July 2016 in “Cosmetics” Future hair cosmetics will be safer and more effective.
34 citations,
January 2011 in “Annals of dermatology/Annals of Dermatology” Using a hair dryer at 15 cm with continuous motion causes less damage than natural drying.
21 citations,
January 2022 in “Biomaterials Science” RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
19 citations,
May 2021 in “Clinical, Cosmetic and Investigational Dermatology” Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.
16 citations,
October 2023 in “Molecular cancer” New treatments like nanotechnology show promise in improving skin cancer therapy.
16 citations,
June 2022 in “Agronomy” Certain natural biostimulants can increase lettuce yield and improve its nutritional content.
15 citations,
January 2023 in “Biomaterials Research” 3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.
14 citations,
September 2021 in “International journal of molecular sciences” Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
13 citations,
April 2019 in “International journal of molecular sciences” Acyzol could help treat conditions caused by zinc deficiency.
12 citations,
January 2020 in “Indian Dermatology Online Journal” Female pattern hair loss has multiple causes and treatments, with new therapies showing promise.
11 citations,
January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft” Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.
11 citations,
March 2021 in “Cleveland Clinic Journal of Medicine” Treating hair loss in both men and women is effective and improves quality of life.
11 citations,
January 2014 in “Egyptian Journal of Dermatology and Venereology” Women losing hair might have lower levels of vitamin D.
10 citations,
August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
10 citations,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
10 citations,
October 2017 in “BMJ Open” The Korean study confirmed that bariatric surgery is effective for weight loss in Asians.
9 citations,
March 2022 in “Antioxidants” Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
8 citations,
January 2019 in “International Journal of Trichology” Early diagnosis and a combination of treatments, including minoxidil and finasteride, are recommended for managing hair loss in India.
7 citations,
December 2022 in “Plants” Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.
7 citations,
August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
7 citations,
December 2021 in “Pharmaceutics” Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
7 citations,
December 2020 in “Endocrine-related Cancer” The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.