67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses telogen effluvium, a common type of hair loss, focusing on differentiation from other conditions and potential causes, but presents no new research findings.
66 citations
,
March 2019 in “Cellular and Molecular Life Sciences” This review discusses melanocyte development, emphasizing the plasticity of melanoblasts and the role of both intrinsic and extracellular signals in their differentiation and migration, with no new clinical results reported.
65 citations
,
May 2010 in “Current Women's Health Reviews” This review discusses oxidative stress's role in polycystic ovary syndrome and examines various biomarkers to understand its impact on the disorder's pathogenesis, but reports no new clinical results.
58 citations
,
January 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study suggests that sexual dimorphism in adipose tissue functions may be linked to androgen levels, as women with PCOS demonstrated a more masculine adipokine expression pattern.
53 citations
,
February 2020 in “Expert Opinion on Pharmacotherapy” This review discusses pharmacologic and non-pharmacologic treatments for androgenetic alopecia, noting that current medications like finasteride and minoxidil can slow hair loss but only partially restore hair growth, with early treatment offering better outcomes.
49 citations
,
August 2007 in “Dermatologic surgery” This review discusses newer therapeutic techniques for treating postacne scarring, highlighting their effectiveness for particular grades of scars, and reports no new clinical results.
48 citations
,
January 2002 in “Dermatology” In this study, hair pain (trichodynia) was reported by a significant portion of patients with hair loss, but it did not correlate with the cause or activity of the condition.
46 citations
,
May 2018 in “Dermatologic Surgery” In this study, subdermal platelet-rich plasma injections significantly increased hair count and shaft caliber in individuals with androgenetic alopecia, with monthly treatments potentially offering greater benefits.
45 citations
,
January 2012 in “International Journal of Trichology” This study reported that trichoscopy is a more effective diagnostic tool than the trichogram for early diagnosis of FAGA, regardless of hair shaft diversity cut-off levels.
44 citations
,
April 2006 in “Expert opinion on drug safety” This review describes the approved use and adverse effects of gefitinib in patients with advanced non-small cell lung cancer, without presenting new clinical findings.
41 citations
,
March 2007 in “Journal of dermatological science” This study found that oral administration of l-cystine with vitamin B6 effectively prevents environmental cigarette smoke-induced alopecia in mice by reducing hair bulb cell apoptosis.
38 citations
,
February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
38 citations
,
May 2006 in “Archives of Gynecology and Obstetrics” This study reported that women with PCOS had higher levels of certain hormones and lower SHBG levels compared to non-PCOS women with similar symptoms, highlighting a less favorable endocrine profile in PCOS cases.
37 citations
,
January 2017 in “International Journal of Dermatology” This study found that trichoscopic features like exclamation mark hairs and angulated hairs were more indicative of alopecia areata in an Asian population, while features like broken hairs of different lengths and flame hairs were more common in trichotillomania.
34 citations
,
October 1994 in “Journal of Pharmaceutical Sciences” This study found that increasing the proportion of ethanol in minoxidil formulations improved skin penetration in both in vitro and in vivo tests on mice.
32 citations
,
August 2015 in “Journal of Investigative Dermatology” In this study using a mouse model, Prom1+ dermal papilla cells were found to regulate the size of the papilla via β-catenin communication but did not aid in dermal repair.
31 citations
,
June 2018 in “Dermatologic Surgery” In this randomized, double-blind trial, researchers observed that low-level laser therapy led to significantly greater hair regrowth on treated areas compared to a sham treatment in patients with androgenetic alopecia over 24 weeks, suggesting it as a potentially effective and safe option.
29 citations
,
September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
28 citations
,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” This review classifies engineered nanomaterials by composition and application in biomedicine, highlighting diverse uses like regenerative medicine and potential occupational side effects, but reports no new clinical results.
25 citations
,
January 2010 in “International Journal of Pharmaceutics” This study found that polymeric nanoparticles retained more minoxidil and facilitated superior drug permeation compared to lipid nanoparticles, although premature drug release affected formulation performance.
25 citations
,
November 2005 in “Facial Plastic Surgery” This article discusses the unique considerations for cosmetic surgery on the Asian male face and reports no new research findings; it emphasizes different psychological approaches and surgical techniques.
24 citations
,
May 2006 in “Proceedings of the National Academy of Sciences of the United States of America” This study reported that heterozygosity for FHIT affects mice's susceptibility to spontaneous alopecia areata and to certain preneoplastic lesions induced by benzo[a]pyrene, but does not change how they respond to budesonide and N-acetyl-L-cysteine.
23 citations
,
May 1998 in “Journal of Dermatological Science” This study suggests that skin sections from 4-week-old C3H mice could serve as an in vitro model for human androgenic alopecia, as minoxidil partially reverses suppressed hair follicle elongation.
19 citations
,
October 2020 in “Journal der Deutschen Dermatologischen Gesellschaft” This review found that despite varied levels of stigmatization reported in studies, hair loss generally leads to stigmatization and a reduced quality of life, but specific research on this stigma is limited.
19 citations
,
July 2020 in “Journal of cancer survivorship” This review discusses the unmet supportive care needs of men and women experiencing chemotherapy-induced alopecia and reports no new results, urging healthcare providers to tailor interventions to individual patient needs.
19 citations
,
October 2011 in “Clinics in Dermatology” This review discusses the cutaneous side effects of chemotherapy, noting that they frequently involve changes to skin, hair, and nails, and reports no new results.
17 citations
,
May 2018 in “Journal of Cosmetic Dermatology” This study reports that nonscarring diffuse hair loss in women is most common in the 21-40 age group, with low serum ferritin, vitamin B12, and vitamin D3 levels contributing to its pathogenesis.
17 citations
,
January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
17 citations
,
July 2014 in “Our Dermatology Online” In this study of elderly patients at an Indian medical center, researchers found that xerosis was the most common physiological skin change and pruritus was the most frequent complaint.
16 citations
,
January 2019 in “Neuropsychobiology” This study found that individuals with lichen planopilaris reported lower quality of life and self-esteem and higher depression scores compared to healthy controls.