research Oxygen, Metabolism, and Regeneration: Lessons from Mice
Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
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research Oncogenic Senescence: A Multi-Functional Perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Skin Organoids: A New Human Model for Developmental and Translational Research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis
Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Tissue Engineering Strategies for Human Hair Follicle Regeneration: How Far From a Hairy Goal?
Fully regenerating human hair follicles not yet achieved.
research Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
research Engineering the Niche for Hair Regeneration: A Critical Review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research Neonatal Finasteride Induces Anxiogenic-Like Profile and Deteriorates Passive Avoidance in Adulthood After Intrahippocampal Neurosteroid Administration
Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
research Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Skin-Derived Stem Cells as a Source of Primordial Germ Cell and Oocyte-Like Cells
Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
research Stem Cells in Dermatology and Anti-Aging Care of the Skin
Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
research Organ Regeneration Based on Developmental Biology: Past and Future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
research A Novel and Safe Small Molecule Enhances Hair Follicle Regeneration by Facilitating Metabolic Reprogramming
Small molecule IM boosts hair growth by changing stem cell metabolism.
research Japan Strengthens Regenerative Medicine Oversight
Japan improved its regulation of regenerative medicine to ensure safety and prevent unproven treatments.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives
Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
research Pre-Aggregation of Scalp Progenitor Dermal and Epidermal Stem Cells Activates the WNT Pathway and Promotes Hair Follicle Formation In Vitro and In Vivo Systems
Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
research Engineering Cell-Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research The Promise and Challenges of Cell Therapy for Psoriasis
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Dental Derived Stem Cell Conditioned Media for Hair Growth Stimulation
Substances from dental stem cells might help treat hair loss.
research Early-Stage Bilayer Tissue-Engineered Skin Substitute Formed by Adult Skin Progenitor Cells Produces an Improved Skin Structure In Vivo
Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
research Mesothelial Stem Cells and Stromal Vascular Fraction for Skin Rejuvenation
Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research The Patch Assay Reconstitutes Mature Hair Follicles by Culture-Expanded Human Cells
The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.
research Targeting the Stem Cell Niche: Role of Collagen XVII in Skin Aging and Wound Repair
Collagen XVII is important for skin aging and wound healing.
research Epidermal Stem Cells: An Update on Their Potential in Regenerative Medicine
Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
research Skin Cell-Derived Extracellular Vesicles: A Promising Therapeutic Strategy for Cutaneous Injury
Skin cell-derived vesicles can help heal skin injuries effectively.