April 2024 in “Lečaŝij vrač” This study found that thrombocytopenia is a common side effect of valproic acid, affecting up to 54% of elderly patients, but it is under-investigated despite significant therapeutic consequences.
January 2024 in “Updates in clinical dermatology” This paper reviews the autoimmune disorder alopecia areata, its progression, and its significant emotional and psychological impact, but reports no new clinical findings.
September 2023 in “Journal of the Dermatology Nurses’ Association” This case study reports that platelet-rich plasma treatment led to total hair regrowth in a 71-year-old woman with alopecia areata who had not responded to previous standard therapies.
April 2023 in “Journal of Investigative Dermatology” This review discusses PRP combination therapies for androgenetic alopecia, acne scarring, and cutaneous rejuvenation, and reports increased effectiveness with combination treatments but highlights the need for more research with standardized protocols.
January 2023 in “Journal of orthopedics & bone disorders” This study suggests that platelet-rich plasma's high levels of growth factors may be limited in promoting bone regeneration due to the concurrent release of Dickkopf-1, which inhibits osteogenesis.
July 2022 in “Journal of Investigative Dermatology” This study suggests that high platelet concentrations in PRP may not be necessary for hair growth in androgenetic alopecia, and certain growth factors might negatively impact clinical outcomes.
April 2022 in “The Egyptian Journal of Hospital Medicine” This review examines the use of platelet rich fibrin for treating post-acne scars and reports no new clinical results; it highlights that fibrin's matrix enables a prolonged release of growth factors.
December 2021 in “Current Issues in Pharmacy and Medical Sciences” This review discusses the use of platelet-rich plasma therapy in aesthetic anti-aging treatment, highlighting its reported safety and effectiveness in skin regeneration, but presents no original clinical results.
This abstract suggests that cost barriers limit the application of standard aesthetic procedures in developing countries, while exploring platelet-rich plasma as a potentially safer and less invasive option in geriatric aesthetics. Detailed results were not reported.
December 2020 in “RUHS Journal of Health Science” This paper discusses the various causes and types of alopecia and presents no original research findings.
September 2020 in “Revista Digital de Postgrado” This review discusses the characteristics and dermatological applications of platelet-rich plasma and fibrin meshes and reports no new clinical results.
July 2018 in “Hair transplant forum international” This study observed significant variation in platelet concentrations across four different platelet-rich plasma (PRP) systems, suggesting that PRP system choice may affect treatment outcomes for hair growth.
PRP therapy is a promising hair loss treatment for people with alopecia.
February 2018 in “Medicine - Programa De Formación Médica Continuada Acreditado” This review discusses current and emerging treatments for androgenic alopecia, noting that minoxidil and finasteride are the only FDA-approved options, while other methods lack comparable evidence of efficacy.
January 2017 in “Hair transplant forum international” In this study, intra-operative platelet-rich plasma during follicular unit extraction for hair transplant was not found to improve hair yield in patients.
June 2016 in “The Egyptian Journal of Forensic Sciences and Applied Toxicology” In this study, long-term occupational exposure to benzene in fueling workers was associated with increased skin diseases, altered blood cell counts, and elevated liver enzyme levels compared to overseers.
January 1994 in “Toxicological Sciences” This study found that chronic high dosages of 2-(difluoromethyl)-dl-ornithine caused various toxicities in rats and dogs, with some effects potentially minimized at lower dosages.
August 1978 in “Dicp-The annals of pharmacotherapy” Mannitol diuresis allows higher doses of cis-platinum for testicular cancer treatment without increasing kidney damage.
June 2020 in “Journal of Investigative Dermatology” This study found that leukocyte-rich platelet-rich plasma appeared safe and may offer some benefits to patients with scarring alopecia, though further research is needed due to the small sample size.
August 2014 in “Journal of clinical & experimental dermatology research” This study outlines a hair regrowth treatment targeting hair follicle stem cells, 5-alpha reductase pathway, and microinflammation using PDGF and VEGF, but reports no clinical results.
2 citations
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January 2019 in “Springer eBooks” The conclusion is that different blood diseases cause specific oral symptoms and require varied treatments to manage these symptoms and improve patient health.
June 2020 in “Journal of Investigative Dermatology” This study found that FDA-cleared devices for preparing platelet-rich plasma showed inconsistent product quality, with variable platelet counts and inadequate quality control performance, suggesting clinical improvement may not rely on platelet concentration.
September 2017 in “Springer eBooks” PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.
January 2013 in “Otorhinolaryngology clinics : an international journal” This review examines platelet-rich plasma's applications in aesthetic surgery and reports no new clinical results; the authors highlight its growing use and potential as a therapeutic modality.
February 1961 in “The Lancet” Some new drugs show potential for treating blood cancers but have serious side effects and need more research.
164 citations
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January 2014 in “Journal of Cutaneous and Aesthetic Surgery” This study found that PRP injections may improve hair density and reduce hair loss in patients with androgenetic alopecia without significant side effects, but further research is needed to confirm efficacy.
119 citations
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January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the use of platelet-rich plasma in various dermatological applications and reports no new clinical results; the authors call for more rigorous trials to confirm its effectiveness.
76 citations
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December 2018 in “Aesthetic Plastic Surgery” This review discusses various aesthetic and regenerative applications of platelet-rich plasma and concludes that it has potential as a safe cosmetic intervention but requires further studies to understand its clinical effects.
48 citations
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May 2023 in “Nature Communications” In a study on muscle regeneration in mice, researchers found that platelet-secreted CXCL7 is crucial for recruiting neutrophils to injury sites, aiding early muscle repair and optimal regrowth, suggesting potential therapeutic uses for boosting muscle healing.
36 citations
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December 2012 in “Dermatologic Surgery” Injecting platelet-rich plasma (PRP) can increase hair growth rate and density in male pattern baldness.