Combining microneedling with platelet-rich plasma enhances skin repair and collagen production but may not offer significant extra benefits.
January 2018 in “Hair transplant forum international” This case report describes two twins with alopecia areata totalis who experienced noticeable hair regrowth following platelet rich plasma injections, suggesting PRP as a potential treatment alternative.
October 2017 in “Indian heart journal” Obesity is an independent risk factor for early coronary artery disease (CAD) and its severity is not affected by age.
March 2017 in “Open access journal of surgery” This review discusses the historical development of platelet-rich fibrin from fibrin glue to platelet-enriched formulations and reports no new clinical results.
October 2015 in “Elsevier eBooks” Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.
January 1993 in “Journal of Dermatological Treatment” This study found that 66% of apparently healthy volunteers had some abnormality on biochemical, hematological, or electrocardiographic testing, highlighting the need for pretreatment evaluations in clinical trials.
December 2022 in “Journal of Dermatology Research” This study found that Platelet Rich Plasma injection improved hair growth in women with Female Pattern Hair Loss compared to placebo, but larger trials are needed to validate these results.
June 2020 in “Aesthetic Surgery Journal” This study found that PRP with high estrogen levels increased hair density more effectively and earlier than autologous PRP in male patients with androgenic alopecia.
January 2019 in “Springer eBooks” This chapter discusses procedural therapies like platelet-rich plasma and low-level light therapy for androgenetic alopecia, but reports no new clinical findings.
May 2004 in “Pediatric Dermatology” Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.
212 citations
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September 2008 in “Journal of The American Academy of Dermatology” This review discusses the various treatment options for male and female pattern hair loss and provides no new clinical results; the authors outline the most effective strategies based on existing evidence.
38 citations
,
September 2019 in “Chinese Medical Journal” This review discusses the cardiovascular risks associated with anabolic-androgenic steroid use and reports that, despite known toxic effects, further research is needed to clarify the causality of these risks.
May 2024 in “International journal of medicine and psychology.” This study found that elderly patients with acute coronary syndrome had higher PRU rates, and ticagrelor showed greater antiplatelet efficacy compared to clopidogrel in this population.
1341 citations
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January 2014 in “Cardiology Research and Practice” Managing metabolic syndrome needs both lifestyle changes and medical treatments.
1057 citations
,
November 2011 in “Annals of Biomedical Engineering” This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.
724 citations
,
April 2004 in “Lancet Oncology” This review summarizes the use and neonatal outcomes of chemotherapy during pregnancy, noting its potential for safe use in the second and third trimesters, and reports no new clinical results.
658 citations
,
June 2003 in “Endocrine reviews” This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.
555 citations
,
April 2002 in “The Lancet” This study found that off-pump coronary surgery significantly reduces in-hospital morbidity compared to on-pump surgery without affecting midterm outcomes in the first 1-3 years after the procedure.
471 citations
,
October 2012 in “Cellular and Molecular Life Sciences” This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.
421 citations
,
January 2015 in “Chemical Society Reviews” This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.
397 citations
,
February 2004 in “British Journal of Dermatology” This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.
374 citations
,
May 2016 in “The Lancet. Diabetes & endocrinology” This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.
349 citations
,
January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.
341 citations
,
November 2009 in “The FASEB Journal” This article reviews the multifunctional roles of calreticulin outside the ER and highlights its impact on wound healing in animal models, but reports no new clinical results.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.
305 citations
,
March 2018 in “International journal of molecular sciences” In this review, the authors summarize classical and recent insights into the biology and treatment of hypertrophic scars and keloids, concluding that while understanding and strategies have advanced, effective prevention and treatments remain unsatisfactory.
295 citations
,
September 2006 in “Cell Cycle” This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.
280 citations
,
July 2018 in “Antioxidants” This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.
276 citations
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December 2017 in “Journal of Dermatological Science” This review discusses the limitations of animal models, particularly mice, in accurately predicting human skin wound healing outcomes and emphasizes understanding species-specific differences in skin characteristics for better translation to clinical settings.
252 citations
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April 2009 in “Seminars in Cell & Developmental Biology” This review discusses the complex role of the immune system in tissue repair and regeneration, highlighting its positive and negative influences but reports no new clinical findings.