July 2022 in “L Endocrinologo” This case report describes a 77-year-old woman with female pattern hair loss and elevated testosterone levels, who showed no improvement with minoxidil and lacked adrenal tumors on imaging.
May 1961 in “Tumori Journal” This study found that vitamin A treatment in rats reduced hyperplastic-dysplastic changes and sebaceous gland hypertrophy associated with 3,4-benzpyrene-induced tumors.
This case series observed that patients with persistent post-COVID-19 symptoms reported considerable improvement after using icosapent ethyl, suggesting potential therapeutic success warranting further research.
1 citations
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February 2023 in “Pediatric Dermatology” This case report of an infant with IPEX syndrome highlights the importance of early recognition and treatment, as the patient experienced severe symptoms and succumbed before stem cell transplantation.
November 2003 in “Aap Grand Rounds” Parents often claim to use more home safety measures than they actually do.
3 citations
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February 2014 in “Anadolu psikiyatri dergisi” This report describes the first known case of alopecia in a 16-year-old patient associated with quetiapine use, which resolved after stopping the medication.
1 citations
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December 2014 in “Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology” This study reports that a 15-year-old with trichotillomania showed improvement with aripiprazole treatment, though no consensus on treatment exists in the literature.
May 2026 in “Commagene Journal of Biology” This review found that anti-aging peptides show promise in cosmeceuticals due to their targeted actions to rejuvenate skin, but challenges like peptide stability, penetration, and limited clinical data limit their current effectiveness.
November 2025 in “Frontiers in Endocrinology” This study indicated that prediabetes may make ovaries more susceptible to PCOS-like changes, with mild hyperglycemia potentially having harmful effects on ovarian health.
51 citations
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August 2021 in “Turkish Journal of Medical Sciences” This review concluded that monoclonal antibodies are currently the most effective treatment for COVID-19, with potential efficacy of high-titer convalescent plasma when used early, while multiple other drugs require further evaluation to determine their effectiveness.
50 citations
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May 2000 in “Fertility and Sterility” This study found that flutamide was more effective than finasteride in reducing hair growth in women with hirsutism over a one-year period.
49 citations
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June 1998 in “Journal of Endocrinological Investigation” In this study, both cyproterone acetate-estrogen combination (Diane®) and finasteride were effective in reducing hirsutism, but Diane® showed greater long-term efficacy and cost-effectiveness.
27 citations
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July 2009 in “Experimental and Clinical Endocrinology & Diabetes” This study found that finasteride significantly improved hirsutism scores in women over 12 months and was well-tolerated with no serious side effects.
18 citations
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January 2003 in “Gynecological Endocrinology” In this study, low-dose finasteride (2.5 mg/day) significantly reduced hirsutism scores in women over 12 months without significant hormonal changes or serious side effects.
December 2021 in “Biomarkers” This study found that men with early-onset male pattern alopecia did not significantly differ from healthy individuals in cardiovascular and metabolic measures, but hsCRP and galectin-3 were linked to cardiovascular risk factors in those with the condition.
May 2018 in “Endocrine Abstracts” SFRP-4 might be an early indicator of diabetes and hypertension in men with androgenic alopecia.
6 citations
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May 2011 in “Journal of Pharmacy Technology” This article discusses the growing trend of repurposing existing medications for innovative therapeutic uses and highlights the need for pharmacy practitioners to be informed about accessing clinical evidence related to these applications, but it reports no new results.
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
51 citations
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October 2002 in “European journal of endocrinology” This study found that both high-dose and low-dose finasteride significantly reduced hirsutism scores in women after 12 months, with the lower dose being safe and cost-effective.
August 2021 in “Pelviperineology” This article discusses the complexity of vulvodynia and highlights the potential effectiveness of Fascial Manipulation therapy in addressing this condition, but it reports no new clinical results.
November 2003 in “Aap Grand Rounds” This study found that a combination of low-dose flutamide and metformin therapy may reverse insulin resistance and reduce fat mass in nonobese adolescents with PCOS.
January 2025 in “Dermatology Practical & Conceptual” Perinevoid alopecia can be effectively treated with non-invasive corticosteroids.
125 citations
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September 2019 in “Journal of Clinical Immunology” This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.
43 citations
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February 2019 in “International immunology” This review examines the role of regulatory T cells in skin immune disorders, highlighting their unique functions in conditions like scleroderma, alopecia areata, and psoriasis, without reporting new clinical results.
40 citations
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March 2019 in “Nature Communications” This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.
24 citations
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March 2018 in “Experimental Dermatology” This review explores the role of regulatory T cells in autoimmune skin disorders like alopecia areata and vitiligo, emphasizing unanswered questions and reporting no new experimental results.
21 citations
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July 2016 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome have elevated cardiovascular risk markers, with levels being higher in obese participants compared to non-obese participants.
1 citations
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January 2009 in “Elsevier eBooks” This article reviews the endocrine changes in anorexia nervosa and bulimia nervosa, highlighting hypoleptinemia as a potential mediator, but does not present any new clinical results.
January 2010 in “CNR Solar (Scientific Open-access Literature Archive and Repository) (Consiglio Nazionale delle Ricerche)” This study found that combining metformin and clomifene citrate improved pregnancy outcomes and reduced miscarriage rates in women with PCOS and infertility undergoing intrauterine insemination.
October 2025 in “Journal of Veterinary Clinics” In this case study, a Pomeranian was diagnosed with vaccine-induced ischemic dermatopathy, where different medication regimens gradually improved hair regrowth, though some lesions persisted after tapering treatment.