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Raspberry ketone may help grow hair and improve skin elasticity.

In this study, DHT was found to inhibit hair growth in mice by decreasing IGF-I production in dermal papillae through reduced sensory neuron stimulation.

This study found that patients with alopecia areata had significantly higher troponin I levels compared to those with female pattern hair loss and healthy controls, suggesting an association with cardiovascular diseases.

In this study, researchers found that mitochondrial complex I plays a crucial role in regulating innate immunity and bone remodeling, with Ndufs4 deletion causing systemic inflammation and osteopetrosis through various metabolic shifts and cellular mechanisms.

The researchers reported that keratin 33A is a structural protein specific to goat cashmere hair, with increased winter expression in high-cashmere-producing breeds.

This study found that cocaine disrupted the relationship between certain brain androgen levels and sexual behavior in male rats, with dose-dependent effects on testosterone metabolism.

This study suggests that human hair follicles may actively suppress natural killer cells, which contrasts with the observed defects in NK cell regulation in alopecia areata.

This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.

This review discusses the roles of interferon-γ and PPAR-γ-mediated signalling in scarring alopecia, suggesting these pathways as potential therapeutic targets, but it reports no new empirical results.

This review discusses emerging research areas in alopecia areata pathobiology, highlighting the potential roles of unconventional immune cells and the need for more targeted therapeutic strategies, but reports no new experimental results.

This study found that prostaglandin receptors are widely expressed in hair follicles, suggesting a complex network of prostanoid pathways involved in hair growth control.

This article reviews the role of vasoactive intestinal peptide in maintaining immune privilege in hair follicles and does not report new findings; the authors propose it as essential for immune homeostasis in alopecia areata.

Targeting MIG and MCP-1 may help treat inflammation in alopecia areata.

This article discusses the immune privilege in hair follicles and suggests that restoring its collapse might be an effective strategy for treating alopecia areata and cicatricial alopecia, but it reports no new clinical results.

The study suggests that immune privilege collapse in bulge cells and the involvement of pro-inflammatory cytokine interferon-γ contribute to hair follicle stem cell loss in lichen planopilaris.

Farudodstat may effectively treat alopecia areata without harming hair follicles.

In this study, the researchers used a human hair follicle model to demonstrate that T cell stimulation can induce an alopecia areata–like phenotype, with cell proliferation and immune privilege collapse; however, the DHODH inhibitor farudodstat partially mitigated these effects by reducing T cell proliferation.

This study found that in an ex vivo model simulating alopecia areata, the DHODH inhibitor farudodstat reduced T-cell proliferation and MHC protein expression in hair follicles, suggesting it may protect against immune privilege collapse without cytotoxic effects.

This research developed new in vitro models for high-throughput screening of drugs that could protect or restore immune privilege in hair follicles, finding that Tofacitinib was effective in preventing inflammation-related marker upregulation, while Tacrolimus and αMSH worked specifically in outer root sheath keratinocytes.

This study found that human hair follicle cells suppress immune activity, with somatostatin playing a significant role, suggesting potential applications for treating inflammatory hair loss conditions.

This study suggests that the neuropeptide CGRP may protect against, but not restore, IFNγ-induced collapse of hair follicle immune privilege in alopecia areata.

This study found that Centipeda minima and brevilin A significantly reduced oxidative stress and inflammation in human dermal fibroblasts, suggesting their potential to protect against skin aging and inflammation.

In this study, researchers observed that the skin quality and hair follicle development of Rex rabbits improved when slaughtered in winter compared to summer, with findings suggesting seasonal regulation via multiple signaling pathways affecting fur characteristics.

This study reported that IL-15 promotes human hair growth and protects hair follicle immune privilege, potentially stabilizing alopecia areata treatment outcomes when selectively stimulating IL-15Rα signaling.

This study suggests that interleukin-15 plays a complex role in alopecia areata, potentially contributing to immune infiltration while also protecting against hair follicle immune privilege collapse and promoting hair growth.

PLGA nanospheres in cosmetics improve skin and hair treatment effectiveness.

This study found that applying a solution containing oil-soluble vitamin C to damaged hair improved hair cuticle condition and water repellency, suggesting a new cosmetic function beyond its known skin whitening effects.

In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.

This study found that applying a topical inhibitor of TGF-β1 may enhance scar maturation and improve the appearance of hypertrophic scars in a nude mouse model after two weeks.

This study suggests that SOCS3 treatment may effectively inhibit alopecia areata by suppressing CD8+ T cell activity and IFN-γ production.