7 citations
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August 2020 in “Plastic and reconstructive surgery. Global open” In this study, QR 678 and QR 678 Neo formulations containing growth factors and peptides were found to be safe in vitro and promoted hair growth in vivo in an animal model, suggesting their potential as treatments for alopecia, including secondary alopecia post-chemotherapy.
This review discusses treatments for androgenic alopecia, noting that current options like finasteride and minoxidil are effective for only 10% of patients, thus highlighting the need for new therapies.
18 citations
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May 2017 in “Head & Neck” This study reported that free tissue transfer for postcranioplasty implant exposure led to a 100% free flap survival rate and salvaged 91% of the implants without removal, suggesting it is a highly effective reconstructive option even for chronic cases.
39 citations
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August 2017 in “Colloids and Surfaces B: Biointerfaces” This study found that 50-nm PLGA nanoparticles delivered with iontophoresis enhanced skin permeation of indomethacin in rats more effectively than 100-nm nanoparticles, suggesting improved targeting of hair follicles.
25 citations
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October 2020 in “BMC Veterinary Research” This study found that low doses of ivermectin cream enhanced wound healing and reduced scarring by modulating inflammation and growth factor levels, suggesting potential topical use for wound treatment.
19 citations
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March 1998 in “Endocrinology” This study found that sex differences in somatostatin biosynthesis in rat hypothalamic neurons develop between postnatal day 1 and 5, influenced by the conversion of testosterone to estrogen.
1 citations
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November 2024 in “Life” In this study, Desmodesmus pannonicus water extract demonstrated significant antioxidative properties, inhibited melanin production, promoted wound healing in human keratinocyte cells, and showed potential for hair growth enhancement in human follicle dermal papilla cells, suggesting its promise for future dermatological applications.
1 citations
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July 2023 in “Al-Azhar Medical Journal” This study observed a significant association between antigliadin antibodies (IgA and IgG) and alopecia areata severity, suggesting that serological tests could help diagnose subclinical celiac disease in these patients, with IgA and IgG showing 100% sensitivity and specificity at specific cutoff points.
1 citations
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November 2022 in “Animals” This study found that differences in skin transcriptomes between juvenile and adult mink, as well as between black and white mink, suggest genes regulating hair color are active during early development rather than adulthood.
September 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This study described trichilemmal cysts, firm lumps that form from blocked hair follicles, typically found on the scalp but also less commonly on other body parts, affecting less than 10% of the population and possibly inherited as an autosomal dominant trait.
December 2024 in “Biomedical & Pharmacology Journal” In this study, researchers developed and assessed two polyherbal hair tonic formulations, finding that Hair Tonic A containing 10% white tea extract improved hair thickness, manageability, and anti-frizz properties, particularly for blonde and black hair, while demonstrating greater stability compared to Hair Tonic B.
November 2023 in “Biology” This study investigated m6A RNA modification in hair follicle development, finding that Hycole rabbits displayed longer hair, higher primary hair follicle ratios, and thicker skin compared to Rex rabbits, while also identifying key differential genes and pathways involved in hair growth.
18 citations
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February 2022 in “Cell Death Discovery” In this study, researchers found that hair follicle-derived mesenchymal stem cells, modified to overexpress extracellular matrix protein 1, significantly improved liver function and reduced liver damage in cirrhotic mice by inhibiting hepatic stellate cell activation and TGF-β/Smad signaling.
18 citations
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November 2016 in “International clinical psychopharmacology” This study found that in a 10-week trial, inositol did not significantly reduce trichotillomania symptoms compared to placebo, although 42.1% of inositol-treated patients felt 'much or very much improved' at the study's end.
10 citations
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September 1997 in “Molecular carcinogenesis” This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.
1 citations
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December 2018 in “Talenta Conference Series Tropical Medicine (TM)” This study evaluated the antifungal activity of lemongrass oil in anti-dandruff gel shampoo formulations and found that a 10% lemongrass oil concentration was the most effective at inhibiting the growth of the dandruff-causing fungus Pityrosporum ovale.
October 2024 in “Irish Journal of Medical Science (1971 -)” Continuous glucose monitoring and GLP-1 receptor agonists improve diabetes management, but personalized care and education are crucial.
85 citations
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January 1996 in “International Journal of Cancer” In this study, AS101 combined with chemotherapy significantly reduced the severity of chemotherapy-induced alopecia in non-small-cell-lung-cancer patients and may involve immune mechanisms related to IL-1 and PGE2.
6 citations
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January 2014 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This case series describes three siblings with hereditary vitamin D-resistant rickets, highlighting variations in their clinical presentations.
December 2022 in “Otorhinolaryngology, Head and Neck Pathology.” This study found that applying photobiomodulation therapy after septoplasty helped reduce pain and mitigate changes in the autonomic nervous system compared to those who did not receive the therapy.
May 2022 in “Голова и шея.” In this pilot study, researchers observed that low-intensity laser radiation at 445±40 nm increased the temperature of gingival tissues in Wistar rats by 8.37°C without exceeding the safety threshold, suggesting potential for clinical trials.
266 citations
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January 2016 in “Development” In this study, researchers found that YAP and TAZ, when localized in the nucleus of basal layer cells, are crucial for skin regeneration and hair growth, with their loss leading to slower cell proliferation, hair loss, and impaired wound healing in mice.
98 citations
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March 2019 in “Frontiers in immunology” This study concluded that heterozygous NFKB2 mutations lead to a distinct and severe form of primary immunodeficiency with early onset, primarily T cell-mediated autoimmunity, and impaired B-cell differentiation.
20 citations
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May 2011 in “Cancer Biology & Therapy” This study found that finasteride decreased DHT-stimulated AR activity and cell growth in prostate cancer cells with mutant AR, but not in those with wild type AR.
12 citations
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June 2013 in “The Prostate” This study found that dutasteride more effectively inhibited androgen receptor signaling and reduced cell growth compared to finasteride in prostate cancer cell models, with varying sensitivities across different cell lines.
February 2021 in “Journal of pharmaceutical and biological sciences” This article reviews multiple treatments for alopecia areata, highlighting their variable efficacy and safety without any being curative; it reports no new clinical findings.
65 citations
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February 2011 in “Molecular cancer therapeutics” This study reported that the novel AKT inhibitor CCT128930 demonstrated significant antitumor activity in human cancer cell lines and xenografts, highlighting its potential as an anticancer therapy.
10 citations
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March 1999 in “Comparative Haematology International” This study found that chronic administration of testosterone in mice induced an elevated EPO secretion response, possibly mediated through DHT, without affecting baseline EPO levels.
January 2026 in “Journal of Dermatology Research and Therapy” This case series found that topical janus kinase inhibitors, along with oral fexofenadine and vitamin D supplementation, significantly reduced disease severity in Black pediatric patients with alopecia areata, demonstrating substantial hair regrowth and minimal adverse side effects.
October 2022 in “Indian journal of anatomy and surgery of head, neck and brain” This study concluded that the inferiorly based nasolabial flap is an effective and reliable option for reconstructing oral cavity defects in patients with oral submucous fibrosis, achieving significant improvements in mouth opening without serious complications.