This study found that tenuazonic acid from Alternaria alternata can cause significant damage to vital organs in mice at low doses and highlights the need for regulatory measures to manage its risk in agricultural products.
15 citations
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August 2020 in “American Journal of Pathology” This study found that insulin promotes corneal epithelial wound healing and nerve recovery in diabetic mice through Wnt signaling, suggesting its potential as a protective factor for diabetic corneal damage.
4 citations
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July 2013 in “Journal of Dermatological Science” This study found that interleukin-10 deficiency in B6 mice led to inflammatory milk production due to maternal stress, causing alopecia and hepatocyte steatosis in pups.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, FOL-026, a peptide based on osteopontin, was shown to promote angiogenesis and stimulate vascular cell proliferation and migration through neuropilin-1, similar to VEGF, suggesting potential therapeutic applications in vascular repair and angiogenesis-related conditions.
1 citations
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January 2021 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.
11 citations
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January 2017 in “Journal of Endocrinology/Journal of endocrinology” This study observed that female mice with disrupted 5α-reductase 1 showed increased insulin resistance and hepatic steatosis, suggesting altered glucocorticoid metabolism contributes to metabolic disorders.
4 citations
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November 2022 in “Frontiers in endocrinology” This study found that intracrine androgen signaling via 5α-reductase is essential for optimal endometrial decidualization and vascular development during this process in mice.
February 2026 in “Frontiers in Endocrinology” In this case study, a woman with congenital adrenal hyperplasia experienced substantial improvement in musculoskeletal and neurobehavioral symptoms after low-dose testosterone therapy, highlighting its potential role in managing chronic glucocorticoid overtreatment effects.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that intracrine androgen signaling, mediated by steroid 5α-reductase, is essential for optimal decidualization and vascular development in the endometrium during pregnancy, indicating potential targets for improving age-related fertility issues.
February 2013 in “Journal of The American Academy of Dermatology” Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.
10 citations
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January 2002 in “Nihon Keshouhin Gijutsushakaishi/Journal of S C C./Nihon Keshouhin Gijutsushakai kaishi” This study found that the cuticle layer of hair contributes approximately 60% to bending stress, highlighting its significant role in the mechanical properties of hair stiffness.
November 2023 in “Scientific reports” This study presents the first report on cloning and characterizing the full-length cDNA of SRD5A1 in Indian catfish (Clarias magur), revealing expression differences across reproductive phases and increased expression post-Ovatide administration in ovaries and testis.
1 citations
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November 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” This study in Pudukottai district found that among 5870 individuals attending rural health camps, 1468 had skin complaints, with non-infectious conditions like eczema being most common, followed by fungal, bacterial, and arthropod infections.
1 citations
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June 2020 in “IP Indian journal of clinical and experimental dermatology” This study found that yellow dots were the most common trichoscopic finding in adult patients with alopecia areata, observed in 88.5% of cases.
May 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” This study examined the clinical patterns and trichoscopic features of female pattern hair loss at a rural tertiary care hospital, but it does not report any specific results.
May 2024 in “IP Journal of Nutrition Metabolism and Health Science” This study found that an educational program significantly improved knowledge about polycystic ovary syndrome and its prevention among adolescent girls at a selected college.
September 2021 in “IP Indian Journal of Clinical and Experimental Dermatology” In this study, Diabliss Hair Water was found to improve hair growth rate, density, and quality while reducing hair fall in healthy adults experiencing hair thinning concerns.
July 2018 in “IP Indian journal of clinical and experimental dermatology” This study examined various causes of hair loss in children and found that factors like malnutrition, poor grooming habits, and stress were common, with acquired non-scarring alopecia being prevalent.
In this study, oral testosterone administered three times daily normalized serum testosterone levels in men with experimentally induced hypogonadism over nine days and significantly reduced SHBG.
26 citations
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December 2006 in “Endocrinology” This study found that a topical cream containing PTH (7–34) significantly stimulated hair growth in hairless mice.
January 2017 in “IP Indian journal of clinical and experimental dermatology” This study found that metabolic syndrome was significantly more common in men with early-onset androgenetic alopecia compared to controls, indicating a potential increased risk of cardiovascular issues in this population.
This study revealed that IP-PA1, derived from Pantoea agglomerans, promoted hair growth in mice and increased certain growth factor expressions in human cell cultures, suggesting a unique mechanism compared to traditional hair growth treatments.
January 2015 in “IP Indian journal of clinical and experimental dermatology” This study found statistically significant associations between female androgenetic alopecia and certain components of metabolic syndrome, such as increased waist circumference and hypertriglyceridemia, in the Kashmiri population.
43 citations
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October 2006 in “Journal of Cell Science” In this study, researchers found that contrary to expectations, keratin 10 domains did not reduce cell proliferation and instead increased tumor development in genetically modified mice.
29 citations
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March 2020 in “Stem Cell Research & Therapy” This study suggests that adipose-derived mesenchymal stem cells from diabetic mice can enhance wound healing by promoting fibroblast growth, migration, angiogenesis, and differentiation into fibroblasts and endothelial cells.
This study found that topical application of Sinsun-yukza-hwan extract significantly increased hair density and thickness in a mouse alopecia model and enhanced expression of growth-related genes.
4 citations
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January 2023 in “Skin health and disease” This study shows that in a mouse model of Alopecia Areata, selective JAK1 inhibition facilitated hair regrowth and inflammation resolution while potentially offering a better safety profile compared to pan-JAK inhibition.
3 citations
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January 2011 in “Annals of Dermatology” This study found that EGFR inhibitors and ligands did not significantly affect the expression of inflammatory biomarkers in cultured sebocytes, except for a notable increase in IL-1 expression with EGF treatment.
In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.
29 citations
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January 1996 in “Journal of Pharmaceutical Sciences” This study developed a theoretical model that suggests finasteride may completely inhibit 5AR type 2, but not sufficiently suppress type 1, leading to only partial reduction of dihydrotestosterone at clinical doses.