October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
October 2010 in “Journal of Men's Health” Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
July 2008 in “Journal of Intellectual Property Law & Practice” This ruling by the UK Court of Appeal allows patents for pharmaceuticals based on new dosing regimens and can override previous decisions to align with European Patent Office practices.
February 1994 in “Archives of Dermatology” This article critiques the limited clinical applicability of recognizing catagen in hair cycle studies, emphasizing its importance in histologic diagnosis and the continuum with telogen effluvium.
April 2016 in “The Journal of Sexual Medicine” This research overview discusses Post-Finasteride Syndrome, presenting data from an FDA database, but it does not report any new clinical findings.
165 citations
,
February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
90 citations
,
January 1979 in “International review of cytology” This chapter reviews the complexity of hair and wool follicle formation, emphasizing the importance of cytological studies to understand the relationship between cellular components.
29 citations
,
December 2017 in “Molecular therapy” This study found that enzyme replacement therapy in mice with a severe form of classical homocystinuria improved metabolic patterns and alleviated many clinical symptoms.
22 citations
,
March 2020 in “Cosmetics” This review discusses the potential of nanotechnology-based formulations for delivering topical minoxidil to improve hair loss treatment outcomes and reports no new clinical results, urging further research into their benefits and safety considerations.
19 citations
,
January 2013 in “Journal of Cutaneous Medicine and Surgery” This study found that patients with alopecia areata exhibit a stronger deficiency in coping with stress compared to those with androgenetic alopecia and controls, suggesting a psychosomatic component to the condition.
8 citations
,
March 2020 in “Metabolites” This study found differences in urinary androgen and estrogen concentrations between male pattern baldness patients treated with finasteride and healthy controls, suggesting potential biomarkers for post-finasteride syndrome.
8 citations
,
January 1987 in “Gynecological Endocrinology” This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.
7 citations
,
June 1967 in “Journal of Investigative Dermatology” This study reports an unusual finding of plucked anagen hairs with intact hair papilla and connective tissue sheath in various scalp disorders, suggesting further documentation is needed.
5 citations
,
September 2021 in “Journal of Medical Biochemistry” This study found that Wet-type Age-Related Macular Degeneration patients had higher oxidative stress and HMGB-1 levels compared to healthy controls, suggesting a link to increased tissue inflammation and necrosis.
2 citations
,
December 2019 in “Neurobiology of Stress” This review discusses the potential link between early postnatal allopregnanolone levels and vulnerability to drug abuse in adulthood, noting a need for more in-depth studies to confirm this relationship.
June 2026 in “International Journal of Ayurveda and Pharma Research” This study documented a case where Ayurvedic treatments for plaque psoriasis significantly reduced the severity of symptoms, as measured by an 84% improvement in the Psoriasis Area and Severity Index score from 6.5 to 1.04.
April 1978 in “Pediatric research” This study found that zinc levels in hospitalized patients with significant weight loss did not correlate with taste perception or vitamin A status, even in those with reduced taste acuity.
510 citations
,
August 2006 in “Endocrinology” This minireview discusses a proposed model of the vitamin D receptor that explains how 1alpha,25(OH)2D3 can mediate both genomic and rapid responses through different ligand shapes and cellular locations, without presenting new research findings.
245 citations
,
March 2012 in “Journal of The American Academy of Dermatology” This review discusses the dermoscopic features of common hair and scalp disorders and reports no new clinical results, aiming to assist dermatologists in diagnosing conditions like tinea capitis and alopecia areata.
232 citations
,
October 2015 in “International journal of molecular sciences” This review discusses the role of epidermal and other adult stem cells in skin repair, focusing on their potential therapeutic applications for non-healing wounds and other skin disorders, but reports no new research results.
218 citations
,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that removing PPARγ specifically from mouse adipose tissue led to severe fat loss, insulin resistance, diabetes, and associated metabolic abnormalities.
207 citations
,
January 2011 in “Dermatologic Therapy” This article discusses the factors involved in optimizing laser hair removal, emphasizing patient selection, laser safety, and understanding laser–tissue interactions, but presents no new clinical findings.
184 citations
,
December 2018 in “Nature Communications” This study demonstrated that enhancing human skin constructs with hair follicles through engineered cell organization and vascularization improved hair growth in immunodeficient mice, suggesting potential advances for treating alopecia and chronic wounds.
143 citations
,
August 1991 in “Endocrinology” This study found that blocking androgen receptors inhibits testicular descent in rats more effectively during the early stages of gubernacular outgrowth than inhibiting 5a-reductase.
125 citations
,
September 2019 in “Journal of Clinical Immunology” This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.
115 citations
,
October 2003 in “Journal of Neuroscience” This study found no evidence supporting the hypothesis that Aβ afferents sprout into the superficial laminas of the spinal cord after nerve injury in rats.
98 citations
,
August 2004 in “BJU international” This review critically examines the current medical management strategies for BPH/LUTS and reports no new experimental results.
96 citations
,
September 2017 in “Analytica Chimica Acta” This review discusses the growing use of scalp hair for elemental analysis in various fields and highlights advancements in analysis techniques, including the future potential of laser ablation ICP-MS, but reports no new clinical results.
94 citations
,
June 2016 in “The FASEB Journal” This review discusses the dual role of the Wnt/β-catenin pathway in mammalian tissue injury, highlighting its potential for both promoting regeneration and contributing to fibrosis, but presents no new findings.
90 citations
,
January 2009 in “Journal of cosmetic and laser therapy” In this study, low-level laser therapy showed no statistically significant improvements in hair growth measures, despite some patients experiencing increases in terminal hairs and shaft diameter.