32 citations
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October 2023 in “Biomedicines” This study found that chronic low-grade inflammation exists independently of excess weight or obesity in women with PCOS, with notable increases in specific cytokines such as IL-9, MCP-3, and MIP-1α.
27 citations
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July 2009 in “Experimental and Clinical Endocrinology & Diabetes” This study found that finasteride significantly improved hirsutism scores in women over 12 months and was well-tolerated with no serious side effects.
21 citations
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October 2011 in “PloS one” In this study, researchers identified three molecules in hair that varied with age, suggesting potential markers for aging and targets for cosmetic products.
18 citations
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January 2003 in “Gynecological Endocrinology” In this study, low-dose finasteride (2.5 mg/day) significantly reduced hirsutism scores in women over 12 months without significant hormonal changes or serious side effects.
4 citations
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January 2019 in “Archives of clinical and medical case reports” Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.
3 citations
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February 2014 in “Anadolu psikiyatri dergisi” This report describes the first known case of alopecia in a 16-year-old patient associated with quetiapine use, which resolved after stopping the medication.
2 citations
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January 2023 in “Sexual Medicine” This study found that the MTCK, a masturbation aid, significantly improved intravaginal ejaculation latency time and some related sexual function scores in men with premature ejaculation after 8 weeks of use.
1 citations
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December 2014 in “Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology” This study reports that a 15-year-old with trichotillomania showed improvement with aripiprazole treatment, though no consensus on treatment exists in the literature.
In this study, subcutaneous injection of mesenchymal stem cell-conditioned medium promoted regeneration of mice skin aged by D-galactose, improving skin thickness, vascularization, and collagen density.
November 2025 in “Frontiers in Endocrinology” This study indicated that prediabetes may make ovaries more susceptible to PCOS-like changes, with mild hyperglycemia potentially having harmful effects on ovarian health.
August 2026 in “European Journal of Endocrinology” This study found that individualized GAHT regimens, including microdosing, effectively improved gender congruence and quality of life for non-binary individuals, but some experienced a decrease in bone mineral density.
May 2026 in “Commagene Journal of Biology” This review found that anti-aging peptides show promise in cosmeceuticals due to their targeted actions to rejuvenate skin, but challenges like peptide stability, penetration, and limited clinical data limit their current effectiveness.
October 2024 in “Journal of the Endocrine Society” This case study describes three young females with hirsutism who were diagnosed with different underlying conditions—late-onset congenital adrenal hyperplasia, idiopathic hirsutism, and polycystic ovary syndrome with ovarian thecosis—highlighting the need for reevaluation if initial treatments are ineffective.
October 2024 in “Journal of the Endocrine Society” This report describes varied causes of hirsutism in young females and highlights the need to revise diagnoses if initial treatments for common etiologies like PCOS do not yield results.
In this study, researchers found a strong association between premature graying of hair and deficiencies in vitamin D and B12, hypothyroidism, and deranged iron profiles, along with higher stress, altered appetite, smoking, and sleep pattern issues, significantly impacting quality of life.
February 2024 in “Journal of Dermatological Science” This study examined the formation of acquired curved hair and found that the fusion of hair matrix cells during follicle regeneration contributes to asymmetric follicle shapes and curved hair, potentially linked to changes in type IV collagen and protein expression levels.
January 2024 in “Journal of dermatology and skin science” In this study, researchers found that applying topical aprepitant, which blocks substance P receptors, significantly reduced facial dermatitis and hair loss in rats experiencing erlotinib-induced skin side effects, highlighting the neurogenic inflammation's role and the protective effect of ROS inhibition.
June 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers used a reporter mouse model to identify and characterize distinct subtypes of dopaminergic neurons in the gut's enteric nervous system, revealing novel populations with potential implications for understanding their roles and vulnerabilities in disease.
This study found a significant association between premature greying of hair and deficiencies in vitamin D, vitamin B12, hypothyroidism, and disrupted iron profiles, alongside lifestyle factors like stress and smoking.
May 2022 in “Голова и шея.” In this pilot study, researchers observed that low-intensity laser radiation at 445±40 nm increased the temperature of gingival tissues in Wistar rats by 8.37°C without exceeding the safety threshold, suggesting potential for clinical trials.
April 2022 in “Dermatologic Therapy” In this study, diode laser treatment showed greater efficacy in reducing facial hair and increasing satisfaction among hirsutism patients with normal levels of DHEAS and DHT, compared to those with deranged levels, although some benefits were observed across both groups.
85 citations
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January 1996 in “International Journal of Cancer” In this study, AS101 combined with chemotherapy significantly reduced the severity of chemotherapy-induced alopecia in non-small-cell-lung-cancer patients and may involve immune mechanisms related to IL-1 and PGE2.
81 citations
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June 2006 in “Experimental Neurology” Neurosteroids may help prevent seizures in epilepsy.
6 citations
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January 2014 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This case series describes three siblings with hereditary vitamin D-resistant rickets, highlighting variations in their clinical presentations.
This review reports that extracts from the plant Eclipta alba, traditionally used in herbal medicine, may promote hair growth by inhibiting TGF-β1 expression and functioning as a 5α-reductase inhibitor, potentially benefiting androgenic alopecia treatment.
February 2024 in “Buletin Veteriner Udayana” In this case report, treatment with ivermectin, antihistamines, vitamin B complex, and sulfur soap reduced skin lesions and itching in a 5-month-old dog diagnosed with demodecosis after 14 days.
December 2022 in “Otorhinolaryngology, Head and Neck Pathology.” This study found that applying photobiomodulation therapy after septoplasty helped reduce pain and mitigate changes in the autonomic nervous system compared to those who did not receive the therapy.
266 citations
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January 2016 in “Development” In this study, researchers found that YAP and TAZ, when localized in the nucleus of basal layer cells, are crucial for skin regeneration and hair growth, with their loss leading to slower cell proliferation, hair loss, and impaired wound healing in mice.
98 citations
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March 2019 in “Frontiers in immunology” This study concluded that heterozygous NFKB2 mutations lead to a distinct and severe form of primary immunodeficiency with early onset, primarily T cell-mediated autoimmunity, and impaired B-cell differentiation.
51 citations
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August 2021 in “Turkish Journal of Medical Sciences” This review concluded that monoclonal antibodies are currently the most effective treatment for COVID-19, with potential efficacy of high-titer convalescent plasma when used early, while multiple other drugs require further evaluation to determine their effectiveness.