2 citations
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November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
May 2024 in “Chemical engineering journal” This study reports that a new minoxidil and epigallocatechin gallate co-loaded ionic liquids system showed superior efficacy in promoting hair regrowth in a mouse model of androgenic alopecia by activating hair follicle stem cells and improving microenvironment conditions, compared to existing minoxidil products.
October 2023 in “Journal of Molecular Liquids” This study demonstrated that imidazole-based ionic liquids, particularly [Emim]DEP, effectively dissolved yak hair keratin, maintaining its structure better than other tested solvents, and also performed well on human hair and goat wool, with consistent performance even after five recycling cycles.
June 2026 in “Advanced Healthcare Materials” In this study, a taurine-based ionic liquid was developed to effectively penetrate the skin barrier and deliver antioxidants to hair follicles, reducing oxidative stress and promoting hair regrowth in an androgenic alopecia animal model.
June 2026 in “International Journal of Pharmaceutics” January 2025 in “Analytical Methods” This study reports the development of a fluorescent ionic liquid that shows high sensitivity and selectivity for detecting dextran sulfate sodium, with potential applications in clinical diagnostics and environmental monitoring.
January 2025 in “SSRN Electronic Journal”
15 citations
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January 2020 in “RSC advances” In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.
November 2023 in “International Journal of Pharmaceutics” This study reported that a novel ionic liquid delivery system combining ferulic acid and finasteride enhanced the solubility, skin permeation, and effectiveness in promoting hair regrowth in androgenetic alopecia mice, suggesting an improved topical treatment approach.
February 2025 in “ACS Applied Materials & Interfaces” This study found that a novel choline-based valproic acid ionic liquid significantly enhances transdermal penetration and promotes hair regrowth without causing irritation or toxicity, offering a promising treatment option for alopecia.
12 citations
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November 2020 in “Pharmacognosy Journal” This study found that 1-butyl-3-methylimidazolium tetrafluoroborate is the optimal ionic liquid solvent for extracting quercetin from Nothopanax scutellarium leaves.
6 citations
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May 2022 in “Journal of Organometallic Chemistry” This study developed a catalytic system using indenyl-molybdenum(II)-bipyridine complexes and ionic liquid solvents to achieve a 95% yield of campholenic aldehyde from α-pinene oxide under mild conditions.
May 2026 in “Waste and Biomass Valorization”
July 2025 in “Pharmaceutics” This review discusses the application of transdermal drug delivery systems for androgenetic alopecia and explores new technologies to enhance drug penetration but reports no clinical results.
June 2015 in “Biomedical and biopharmaceutical research” This article reviews EU cosmetic product claim regulations and highlights increased harmonization and enforcement while reporting no new results.
October 2014 in “Microscopy” This study found that using ionic liquid for specimen preparation allowed for observation of dermal papilla cells and their cilia in near-living conditions, reducing damage typically caused by conventional preparation methods.
1 citations
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January 2025 in “Molecules” This review reported that while glycyl-L-histidyl-L-lysine tripeptide copper complex (GHK–Cu) has limited skin permeation when used alone, liposomes may enhance its absorption, but there is limited research on this aspect, highlighting a need for further studies.
36 citations
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October 2014 in “Langmuir” This study concluded that bleach treatment partly transforms the hydrophobic top layer of human hair cuticles into a hydrophilic surface with clustered cysteic acid, visualized at the nano-scale using dynamic Chemical Force Microscopy.
6 citations
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March 2018 in “Journal of Chromatography A” This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.
260 citations
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January 2019 in “Pharmaceutics” This study highlights that niosomes, or non-ionic surfactant based vesicles, offer an advantageous drug delivery system due to their stability, cost-effectiveness, and ability to enhance drug bioavailability and targeting efficiency for various therapeutic agents.
2 citations
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November 2009 in “Korean journal of chemical engineering” This study found that the nonionic surfactant Brij 78 stabilized cationic minoxidil microparticles against aggregation, maintaining their substantivity in the presence of excess anionic surfactant.
12 citations
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October 1954 in “Textile Research Journal” This study found that alkali bromide solutions are absorbed into hair depending on salt activity, and the presence of the salt increases water absorption compared to normal conditions.
14 citations
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January 2025 in “AAPS PharmSciTech” This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.
8 citations
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July 2012 in “Annals of biomedical engineering” This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.
2 citations
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April 2008 in “Journal of Dispersion Science and Technology” This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.
27 citations
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April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
17 citations
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June 2021 in “Molecules” This review summarizes the promising role of melatonin combined with nanosized carriers in drug delivery, suggesting enhanced effectiveness in treating various diseases compared to free melatonin.
14 citations
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May 2005 in “Farmaco” This study developed a high performance capillary electrophoresis method, validated for both legal and illicit minoxidil-based products, to confirm minoxidil's presence alongside known impurities.
November 2025 in “Journal of Laboratory Medicine” This study found that cortisol levels, a biomarker of chronic stress, significantly increased in the post-COVID-19 lockdown period compared to pre-lockdown and during-lockdown periods, especially among females and young adults, reflecting sustained psychological stress from the pandemic.
1 citations
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May 2025 in “Carbohydrate Polymers” The new chitosan dressing heals wounds better and faster than current products.