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Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The Rotterdam Study aims to understand various diseases in older adults.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

High androgen levels in young women with PCOS are linked to higher blood pressure.

CDP is crucial for lung and hair follicle cell development.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Finasteride helps hair growth but may cause sexual side effects.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Aging causes skin stem cells to work less effectively.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.