In this report, a 51-year-old woman with systemic lupus erythematosus presented with recurrent joint pain and irregular patches of hair loss, raising differential diagnoses of androgenetic alopecia, lupus-related alopecia, or seborrheic dermatitis.
July 2022 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” This study found that among women with hirsutism, the most common type of non-scarring alopecia observed was androgenetic alopecia with telogen effluvium.
Trichoscopy is a useful tool for monitoring hair and scalp diseases.
58 citations
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July 2018 in “Journal of Allergy and Clinical Immunology” Alopecia areata severity is linked to increased TH1 and TH2 activity.
6 citations
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January 2019 in “Journal of lasers in medical sciences” This study found that using a fractional CO2 laser in combination with minoxidil significantly increased hair count and thickness in Egyptian men with androgenetic alopecia.
January 2026 in “Dermatologic Therapy” In this review, BTXA treatment was reported to effectively increase hair density and improve follicle health in androgenetic alopecia patients by enhancing scalp blood flow and reducing inflammation, without significant adverse effects.
November 2025 in “Cosmetics” This review discusses the clinical efficacy, safety, and mechanisms of Autologous Micrografting Technology for androgenetic alopecia, reporting significant short-term improvements in hair density and thickness.
February 2025 in “Dermatology and Therapy” This study highlights alopecia areata incognita as a unique form of alopecia areata that shares features with telogen effluvium and may relate to androgenetic alopecia, noting its sudden onset and favorable response to topical steroids.
January 2018 in “Dermatology Online Journal” This review discusses current pharmacological proposals for treating alopecia areata, highlighting the need for individualized treatment plans due to limited clinical trial evidence and potential for spontaneous remission.
November 2022 in “Annals of Translational Medicine” This study identified four hub genes that are closely linked to the causative factors of androgenetic alopecia, suggesting potential diagnostic and therapeutic targets.
290 citations
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August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
74 citations
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October 2012 in “The American Journal of Human Genetics” This study found that loss-of-function mutations in the HOXC13 gene cause autosomal-recessive pure hair and nail ectodermal dysplasia, emphasizing its role in hair and nail development.
46 citations
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April 2020 in “Drugs” Emerging therapies like JAK inhibitors show promise for hair regrowth in alopecia areata.
40 citations
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December 2014 in “Indian Journal of Dermatology” This study found that trichoscopy can effectively differentiate scalp psoriasis from seborrheic dermatitis by identifying specific trichoscopic patterns such as hidden hairs, signet ring vessels, and comma vessels.
27 citations
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January 2016 in “Indian Dermatology Online Journal” This article discusses the advantages and different techniques of dermoscopy for skin lesion visualization and reviewing no new clinical results; it emphasizes the integration of polarized light and the importance of training.
25 citations
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March 2021 in “Australasian Journal of Dermatology” This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.
23 citations
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October 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This consensus report outlines Brazilian dermatologists' recommendations for treating alopecia areata, highlighting intralesional corticosteroids for localized cases and systemic therapy for extensive, active disease, along with monitoring side effects.
12 citations
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January 2019 in “International Journal of Trichology” This study found that trichoscopy revealed significant differences in certain variables, such as the brown peripilar sign and white peripilar sign, which may aid in diagnosing early and late stages of androgenetic alopecia.
11 citations
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June 2017 in “Mathematical Medicine and Biology A Journal of the IMA” This mathematical model of alopecia areata illustrates how inflammatory autoimmune responses interrupt the anagen phase of hair growth, and may help evaluate treatments and identify new therapeutic targets.
9 citations
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December 2021 in “Molecules” This study found that certain metabolites from the plants Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana may support hair follicle growth by promoting dermal papilla cell proliferation, supporting their traditional use in hair care.
9 citations
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January 2025 in “Droplet” This review explores recent advancements in precise cell manipulation technologies, detailing the status, principles, benefits, limitations, and future potential of methods like single-cell manipulation and 3D bioprinting for cells and tissue engineering.
9 citations
,
August 2021 in “Journal of clinical medicine” This review discusses pili torti, a rare hair shaft disorder, and reports no new clinical results; it emphasizes the need to investigate underlying conditions in affected individuals.
8 citations
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January 2020 in “International Journal of Trichology” The authors concluded that trichoscopy is a valuable noninvasive tool for diagnosing and monitoring nonscarring alopecia, aiding in the identification of new hair signs in difficult cases.
8 citations
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January 2020 in “PeerJ” This study found significant structural and compositional differences in hair affected by alopecia areata compared to healthy hair, using a range of physico-chemical investigation methods.
7 citations
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October 2023 in “BMC Genomics” In this study, researchers used transcriptome sequencing to identify various noncoding RNAs in the skin tissues of Jiangnan cashmere goats and found that certain long noncoding RNAs may play a role in regulating cashmere fiber fineness, offering new insights for breeding programs.
6 citations
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June 2012 in “PloS one” This study identified a novel SCF mRNA splice variant in white merino sheep skin, which may play a role in hair follicle melanogenesis.
6 citations
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December 2022 in “Cell reports” This study found that feeding mice a high-fat diet with fish oil leads to hair loss through a mechanism involving omega-3 fatty acids and TNF-α signaling, with epidermal fatty acid binding protein playing a key role.
5 citations
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May 2022 in “Molecules” This article reviews the literature on the off-label use of botulinum toxin for dermatological conditions, highlighting its potential effectiveness in treating rosacea, anal fissures, Raynaud phenomenon, hypertrophic scars, keloids, and hidradenitis suppurativa.
5 citations
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September 2021 in “Frontiers in Cell and Developmental Biology” This study found that 3D-cultured dermal papilla cells more accurately mimic in vivo conditions compared to 2D cultures, enhancing our understanding of molecular mechanisms in androgen-induced alopecia.