Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers identified a cluster of hair-specific keratin-associated protein genes within the 21q22.3 region, revealing a novel transcription mechanism involving TSPEAR/C21orf29 that may bypass typical transcriptional termination sites.

This study identified a mutation in the steroid-binding domain of the androgen receptor gene associated with complete androgen insensitivity syndrome, impairing male sexual development due to altered androgen receptor protein function.

This study found that hair curvature in merino wool is influenced by differences in cell type length rather than the proportions of orthocortical and paracortical cells.

This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.

This study found that transient non-lethal levels of endogenous ROS in cultured human hair follicles promoted entry into the growth phase by activating the hair follicle stem cell niche.

This study observed that estrogen receptor β and androgen receptor expressions in the skin decline with age, more noticeably under sun exposure, suggesting a role in skin aging.

Genetics, hormones, and microbiome changes contribute to hidradenitis suppurativa.

This study reports the development of a novel protocol to purify human TRPV3 ion channels, revealing functional properties and differences in ligand interactions, enabling further structural and functional research.

This study suggests that both age and photoexposure may decrease maximum viable epidermis thickness and impact the dermal-epidermal junction in women with Fitzpatrick skin types II-III.

This review investigates how various intrinsic factors—such as growth factors, cytokines, chemokines, and interferons—regulate hair growth through evidence gathered from in vitro and in vivo studies, highlighting the need for further research in human subjects to validate these findings.

This study explored a mother and daughter with loose anagen hair syndrome linked to wooly hair, identifying an intronic variant in the KRT71 gene that affects hair keratin splicing, thus broadening the spectrum of KRT71-related disorders.

This review explored the causes of hair graying and evaluated how plant-derived extracts and phytochemicals might alleviate it, noting that certain compounds showed potential in enhancing melanocyte function, reducing oxidative stress, and influencing stress-related pathways based on experimental evidence.

Bioengineered skin models aging well, useful for studying aging and testing treatments.

This study found that in Arabidopsis seedlings, tonoplast intrinsic proteins are targeted to the vacuole via at least two pathways, including pathways with differing sensitivity to a chemical inhibitor that affect root hair growth and PIN2 targeting.

This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.

This article introduces a hypothesis that the enzyme catalase in processed meats may be a probable cause of higher cancer incidence due to its emission of electromagnetic fields, but no new clinical results are provided.

This study explored the effects of red ginseng-derived components on aging skin cells and found they do not have senolytic properties but can alleviate signs of cellular aging and improve skin cell function by reducing senescence markers and inflammation.

This article introduces a hypothesis linking the enzyme catalase in processed meats to higher cancer incidence due to its electromagnetic field emissions, but reports no new clinical results.

This research found that Foxc1 is critical for maintaining quiescence in activated hair follicle stem cells and that the cancer cell-of-origin influences tumor heterogeneity in mouse skin squamous cell carcinoma.

In this case-control study, the researchers found no significant association between IL-4 VNTR intron 3 and TNF-α (rs1799964) gene polymorphisms and alopecia areata susceptibility among the Egyptian population.

This study found that IL-4 VNTR intron 3 and TNF-α (rs1799964) gene polymorphisms do not have a significant association with alopecia areata susceptibility in the Egyptian population.

This study found that intron 3 VNTR polymorphism in the IL-4 gene may be associated with an increased risk of alopecia areata in the Turkish population.

This study suggests that controlling light exposure can influence cashmere growth by triggering hair follicles to enter their active growth phase sooner, potentially involving the CSDC2 gene as a key regulator.

This study identified a regulatory element necessary for Foxn1 expression specifically in mouse thymic epithelial cells, crucial for thymus development but not affecting hair follicles.

This review discusses current airway regeneration research efforts and reports no new experimental results, highlighting the need for clinical interventions to enhance airway repair.

This article reviews the digitization of historical issues of the Journal of Investigative Dermatology, highlighting the impact and citation durability of its 1970 publications; it reports no new clinical results.

This review highlights the promise of non-viral gene delivery systems, particularly genosomes, over traditional viral vectors due to enhanced safety and efficiency in therapeutic nucleic acid delivery for genetic diseases like cystic fibrosis and malignancies.

This manuscript proposes a hypothesis that the enzyme catalase added to processed meats may emit electromagnetic fields and contribute to cancer development.

This study reports the demonstration of electromagnetic energy transfer from human blood tissue to a human hair follicle through a 1 mm glass barrier, using in vitro experiments.

This study demonstrates that genome-edited epidermal stem cells can continuously monitor blood glucose levels in vivo and potentially aid in diabetes treatment through skin somatic gene therapy.