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The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Fat cells in the skin help start healing and form important repair cells after injury.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Fullerenes show potential in skin care but need more safety research.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Minoxidil and finasteride effectively treat hair loss.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Stem cells from hair follicles can safely treat hair loss.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Advanced human skin models improve drug development and could replace animal testing.