5 citations
,
January 2018 in “Javma-journal of The American Veterinary Medical Association” This case report documents the first successful management of accidental minoxidil toxicosis in a dog, resulting in full recovery after treatment with supportive care, including medications for blood pressure and potential toxicity mitigation.
9 citations
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November 2017 in “International Journal of Nanomedicine” This animal study found that intravenous administration of anionic squarticles, a lipid nanoemulsion, increased survival rates in rats with amitriptyline overdose by mitigating adverse effects and restoring normal blood pressure, highlighting its potential as a detoxifying antidote.
12 citations
,
April 2023 in “Pharmaceutics” This review covers the current and potential medical uses of semifluorinated alkanes, including applications in eye surgery, drug delivery, and oxygen transport.
29 citations
,
September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
2 citations
,
August 2021 in “Journal of pharmaceutical research international” This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.
59 citations
,
October 2012 in “Pharmaceutical Research” This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.
10 citations
,
January 2024 in “Polymer Chemistry” This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.
February 2024 in “International Journal For Multidisciplinary Research” This review examines the advances in nanostructured lipid carriers for treating hyperpigmentation but presents no new clinical results; the authors highlight their potential benefits and applications.
21 citations
,
December 2012 in “European journal of pharmaceutics and biopharmaceutics” This study suggests that using particle-bound antiseptics may provide more effective and longer-lasting skin antisepsis compared to their non-particulate forms.
47 citations
,
September 2015 in “Journal of Drug Delivery Science and Technology” This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.
26 citations
,
May 1984 in “Journal of Parenteral and Enteral Nutrition” In this study, a 54-year-old woman with short bowel syndrome developed biotin deficiency and associated symptoms while on home parenteral nutrition lacking biotin, which improved significantly after supplementation.
1 citations
,
January 2023 in “Journal of pharmaceutical and biological sciences” This review examines ethosomal structures and their mechanisms as skin delivery systems, outlining preparation methods and applications but presents no new experimental findings.
1 citations
,
June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that a cimetidine 10% cream with sodium lauryl sulphate significantly increased drug diffusion through mouse skin and showed promise in treating warts in a preliminary clinical trial.
13 citations
,
December 2008 in “Veterinary dermatology” This study found that a combination of ciclosporin and Miglyol 812 was effective in treating sebaceous adenitis in rabbits, with significant improvement in skin condition and hair regrowth.
23 citations
,
January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
17 citations
,
June 2021 in “Molecules” This review summarizes the promising role of melatonin combined with nanosized carriers in drug delivery, suggesting enhanced effectiveness in treating various diseases compared to free melatonin.
4 citations
,
July 2025 in “International Journal of Nanomedicine” This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.
November 2024 in “International Journal of Research and Review” This review explores the application of nanotechnology in cosmetics, highlighting its role in enhancing skin penetration, sustaining drug action, and protecting against UV radiation, while also addressing regulatory considerations and potential exposure routes.
559 citations
,
October 2020 in “Frontiers in Molecular Biosciences” This review reports on the current state and potential of solid lipid nanoparticles for drug delivery, emphasizing their safety, biocompatibility, and ease of production, and highlights challenges in translating them to clinical practice, including active clinical trials.
92 citations
,
April 2021 in “Pharmaceutics” This review discusses the applications and challenges of lipid nanosystems in various fields, comparing techniques for evaluating nanoparticle properties, and reports no new experimental results.
41 citations
,
September 2021 in “Materials” This review discusses the role of biomaterials and colloidal drug delivery systems in promoting tissue regeneration within regenerative medicine, but it reports no new clinical results.
33 citations
,
January 2001 in “Critical care clinics” This article reviews the roles and synthesis of essential long-chain fatty acids in the body and reports no new research findings; it emphasizes the importance of dietary sources for these lipids.
June 2023 in “International Journal for Research in Applied Science and Engineering Technology” This research highlights the potential of emulgel as an advanced topical drug delivery system, offering improved efficacy for hydrophobic medications in treating dermatological conditions and a range of ailments with its dual release control mechanism of gel and emulsion.
54 citations
,
June 2020 in “Pharmaceutics” This review discusses the advancements in using "soft" colloidal nanocarriers for delivering photosensitive agents and highlights their potential applications in treating diseases like cancer, but it reports no new clinical results.
August 2025 in “MedComm – Biomaterials and Applications” This review highlights recent advances in liposome-based transdermal drug delivery systems, emphasizing their potential to improve drug penetration for both skin and systemic diseases while discussing the challenges and future directions in this field.
6 citations
,
January 2025 in “Molecules” This review highlights the challenges in developing nano-scale drug delivery systems for natural antioxidants in wound healing, pointing out issues like low solubility and skin permeability, and discusses potential solutions such as combining polymers and lipids to enhance delivery effectiveness.
January 2025 in “Pharmaceuticals” This review discusses the role of nanocarrier systems, such as nanoemulsions and liposomes, in delivering antioxidants into the skin to counteract oxidative stress, highlighting recent advancements in topical antioxidant therapy through nanotechnology.
5 citations
,
December 2023 in “Materials” This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.
March 2026 in “Pharmaceutics” This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.
December 2023 in “Journal of the Endocrine Society” In this study, the researchers found that glucocorticoid receptor activation may influence glucose metabolism, with preventive GR antagonist treatment reducing hyperglycemia and restoring glucose tolerance in a PCOS mouse model.